LC/MS/MS Analyst

AmSpec Group; Houston (TX); On-site; USD 60,000 - 85,000; Full time

Job summary

AmSpec Group in Houston is seeking an LC/MS/MS Analyst to perform environmental sample analysis, including preparation, instrument operation, data review, and quality control to deliver accurate results.

You will follow SOPs, maintain records in LIMS, and work with QA and supervisors to address deviations while meeting holding times.

Qualifications

• Bachelor's degree in chemistry, environmental science, or related field; equivalent combination of education and experience considered.
• Experience operating LC/MS/MS and reviewing analytical data.
• Working knowledge of sample preparation, calibration, internal standards, and QC practices.
• Strong troubleshooting, organizational, and time management skills.
• Ability to maintain accurate records, follow written procedures, and communicate clearly.
• Ability to work independently while collaborating with analysts, supervisors, and QA personnel.

Responsibilities

• Prepare and analyze environmental samples, including water and soil, following SOPs.
• Prepare calibration standards, internal standards, reagents, and QC samples with traceability.
• Operate LC/MS/MS instruments, build sequences, and perform calibration checks.
• Review chromatograms, peak integrations, and analytical results for accuracy.
• Evaluate QC results against acceptance criteria and document corrective actions.
• Perform routine instrument maintenance and troubleshoot sensitivity, chromatography, and carryover issues.
• Enter and review data in LIMS and maintain complete lab records.
• Prioritize work to meet holding times and reporting deadlines; communicate delays to supervisor.
• Follow laboratory safety, chemical handling, and waste disposal procedures.

Skills

LC/MS/MS operation

Data review

Record keeping

Troubleshooting

Time management

Independent work

Education

Bachelor's degree in Chemistry or Environmental Science

Tools

LIMS

Data processing software

Job description

Position Summary

We are seeking an LC/MS/MS Analyst to perform environmental sample analysis using liquid chromatography-tandem mass spectrometry. This position is responsible for sample preparation, instrument operation, quality control, and data review to ensure accurate and timely results. The ideal candidate has strong analytical skills, attention to detail, and experience working in a laboratory environment.

Key Responsibilities

• Prepare and analyze environmental samples, including water, soil, and other applicable matrices, following approved analytical methods and laboratory standard operating procedures.
• Prepare calibration standards, internal standards, reagents, and quality control samples, maintaining accurate preparation and traceability records.
• Operate LC/MS/MS instruments, build analytical sequences, and perform required calibration and instrument performance checks.
• Review chromatograms, peak integrations, compound identification, calculations, and analytical results for accuracy.
• Evaluate quality control results against established acceptance criteria; investigate failures and document corrective actions before results are released.
• Perform routine instrument maintenance and troubleshoot issues involving sensitivity, chromatography, contamination, and carryover.
• Enter and review analytical data in the Laboratory Information Management System (LIMS) and maintain complete laboratory records.
• Prioritize assigned work to meet sample holding times and reporting deadlines, communicating delays or technical concerns to the supervisor.
• Follow laboratory safety, chemical handling, housekeeping, and waste disposal procedures.

Qualifications

Required Skills

• Bachelor’s degree in chemistry, environmental science, or a related scientific discipline; an equivalent combination of relevant education and laboratory experience may be considered.
• Previous experience operating LC/MS/MS instrumentation and reviewing analytical data.
• Working knowledge of sample preparation, calibration, internal standards, and laboratory quality control practices.
• Strong troubleshooting, organizational, and time management skills.
• Ability to maintain accurate records, follow written procedures, and communicate clearly.
• Ability to work independently while collaborating with analysts, supervisors, and quality assurance personnel.

Preferred Experience

• Environmental laboratory testing, including PFAS or other trace organic analyses.
• Sample extraction and cleanup techniques.
• Familiarity with LIMS and instrument data processing software.