Large Molecule Bioanalysis Scientist

Medpace; Cincinnati (OH); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Competitive compensation

Comprehensive health benefits

On-site parking

Occasional WFH after training

Job summary

Medpace is actively seeking a full-time, office-based Analytical Chemistry Scientist to join our Bioanalytical Lab in Cincinnati, Ohio. You will work with a team to develop and validate ligand binding assays for large molecule biologics, and draft study protocols, acquisition methods and study reports.

Ideal candidates hold a PhD in a related field and have experience with PK, ADA/NAb analyses, ELISA/ECL/Flow Cytometry, and GLP practices.

Qualifications

• PhD in a related field required.
• Experience with large molecule biomarker analysis.
• Strong project management, compliance, communication and people skills.

Responsibilities

• Develop and validate ligand binding assays for large molecule biologics.
• Draft study protocols/plans, acquisition methods, and study reports.
• Supervise all phases of bioassays for PK, PD biomarkers and immunogenicity studies.
• Supervise technicians for method development, validation and sample analysis.
• Communicate with internal and external resources for sample receipt, QA/QC, sponsor correspondence.

Skills

Project management

Compliance

Communication

People skills

Education

PhD in Cell or Molecular Biology, Immunology, Biochemistry, or related field

Tools

ELISA

ECL

Flow Cytometry

Real-time PCR

Job description

Job Summary

Our corporate activities are growing rapidly, and we are currently seeking a full-time, office-based Analytical Chemistry Scientist to join our Bioanalytical Lab team. This position will work on a team to accomplish tasks and projects that are instrumental to the company’s success. If you want an exciting career where you use your previous expertise and can develop and grow your career even further, then this is the opportunity for you.

Responsibilities

• Develop and validate ligand binding assay (LBA) methods for large molecule biologics;
• Draft study protocols/plans, acquisition methods, and study reports;
• Supervise all phases of bioassays to support human pharmacokinetics, PD Biomarkers and Immunogenicity studies;
• Supervise technicians for performing method development, validation, and sample analysis;
• Communicate with internal and external resources for sample receiving, quality control, quality assurance, sponsor correspondence etc.

Qualifications

• PhD in Cell or Molecular Biology, Immunology, Biochemistry, or related field;
• Previous experience with large molecule biomarker analysis (such as proteins, DNAs, and miRNA, etc.);
• Strong project management, compliance, communication, and people skills;
• Experience with monoclonal antibody (mAb) and antibody drug conjugates (ADC) PK analysis, anti-drug-antibody (ADA) and neutralizing antibody (NAb) analysis;
• Experience with ligand-binding assays such as ELISA, ECL, Flow Cytometry, real time-PCR,etc.;
• Direct working experience in Good Laboratory Practices is preferred.

Medpace Overview

Medpace is a full-service clinical contract research organization (CRO). We provide Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through its scientific and disciplined approach. We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, employing more than 5,000 people across 40+ countries.

Why Medpace?

When you join Medpace, you become part of an innovative team that brings cutting-edge therapies to market while building a meaningful and rewarding career focused on scientific excellence and improving patient outcomes around the world through continuous learning and cross-functional collaboration.

Purpose-Driven Work

• Work alongside physicians, scientists, and industry-leading experts committed to advancing the global development of medical therapeutics through clinical research excellence

Collaborative Culture

• Contribute to an interactive team environment that empowers decision making, creative thinking, and continuous learning through open communication and mutual trust.
• Leadership throughout Medpace is both accessible and approachable

Continuous Growth & Development

• Office based environment with on-site mentors
• Defined career paths with clear advancement opportunities
• Industry renowned onboarding and training programs designed to accelerate professional development
• Ongoing training and continuous learning opportunities throughout your career
• An environment that encourages employees to influence change, contribute ideas, and grow quickly

Other Employee Benefits

• Competitive compensation programs that recognize and reward performance
• Comprehensive health, wellness, retirement, and PTO benefits
• Office based culture with occasional WFH that provides flexibility for eligible positions after training
• Company-sponsored social events and intramural sports

Cincinnati Headquarters Experience

• A modern corporate campus designed to support collaboration and productivity
• Multiple on-site dining options in the heart of Madison Square
• Free on-site parking
• Convenient access to on-site 24-7 fitness and wellness facilities