Laboratory Supervisor, ADMETox: Lead & Develop Cell Labs

Eurofins DiscoverX; Saint Charles (MO); On-site; USD 85,000 - 120,000; Full time

Benefits offered by this job

Medical, dental, vision coverage

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services is actively seeking a Laboratory Supervisor to lead a talented ADMETox team and oversee critical laboratory operations supporting drug discovery and development. The role combines scientific leadership with hands-on experimentation, team mentorship, and strategic planning to ensure studies are executed with the highest quality and on schedule.

Commensurate with experience, this position offers a comprehensive benefits package and stability in a growing

Qualifications

• Bachelor’s degree with 6 years of relevant experience; master’s with 4 years; or Ph.D. with 2 years.
• 3+ years of direct experience with cell-based toxicology assays in a CRO or industry lab.
• Demonstrated experience leading laboratory operations and scientific teams, including workload planning, technical troubleshooting, training, and performance management.
• Experience leading client projects or contract research services from planning through execution and reporting.
• Experience developing, validating, or transferring bioanalytical methods per FDA, ICH, or OECD guidance.
• Proven ability to lead laboratory troubleshooting, process improvement, and method or portfolio expansion in an industry setting.
• Experience leading cross-functional teams, projects, or process-excellence initiatives.
• Hands-on experience with LC-MS, LC-UV, high-throughput analytical method development, or high-resolution mass spectrometry in ADME/DMPK or biotherapeutics applications.
• Technical knowledge of metabolomics as applied to pharmaceutical drug metabolism.
• Project management experience and a track record of leading laboratory operations with limited oversight.

Responsibilities

• Lead daily laboratory operations, balancing people, equipment, schedules, and priorities to meet client commitments, quality standards, and turnaround expectations.
• Work hands-on alongside the team to support cell-based assays, high-content imaging, high-throughput screening, and related ADMET laboratory activities.
• Coach and develop laboratory staff through clear expectations, technical guidance, training, competency assessment, performance feedback, and career development.
• Forecast workload and resource needs; coordinate coverage and adjust priorities to maintain business continuity and on-time delivery.
• Ensure laboratory activities comply with approved procedures, quality requirements, client contracts, Environmental Health and Safety standards, and applicable regulations.
• Maintain strong document and data controls, including SOPs, batch records, study data, client deliverables, quality review, and record-retention requirements.
• Monitor performance metrics, identify risks and constraints, and lead practical process improvements that increase quality, productivity, and operational reliability.
• Manage and maintain a compliant BSL-2 cell-culture laboratory and promote aseptic technique, cleanroom practices, and a strong culture of safety.
• Oversee laboratory equipment and automation platforms, including evaluation, validation, qualification, maintenance, acquisition, implementation, and lifecycle planning.
• Manage laboratory supplies, inventory, storage, departmental expenses, rebilling support, and financial audit obligations.
• Partner with clients, Study/Technical Directors, Client Services, Product Management, and cross-functional teams on project planning, execution, reporting, interpretation, and issue resolution.
• Provide timely, decision-ready communication on project status, assay requirements, risks, constraints, and escalations to internal and external stakeholders.
• Support method development, portfolio expansion, site research and development objectives, and other strategic laboratory initiatives.

Skills

Cell-based assays

Leadership

Quality systems

Project management

Regulatory knowledge

Laboratory operations

Education

Bachelor's degree

Master's degree

Ph.D.

Tools

LC-MS

LC-UV

High-throughput screening

Bioanalytical method development

Job description

Eurofins USA Discovery Services is actively seeking a Laboratory Supervisor to lead a talented ADMETox team and oversee critical laboratory operations supporting drug discovery and development. The role combines scientific leadership with hands-on experimentation, team mentorship, and strategic planning to ensure studies are executed with the highest quality and on schedule.

Commensurate with experience, this position offers a comprehensive benefits package and stability in a growing