Scientist I - ADME Tox

Eurofins DiscoverX; Saint Charles (MO); On-site; USD 65,000 - 90,000; Full time

Benefits offered by this job

Medical benefits

Dental and vision

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services is seeking a Scientist I to support ADME‑Tox projects. You will develop LC-MS methods, lead junior scientists, and ensure quality in analytical workflows within a CRO/industry lab environment.

The role emphasizes method development, validation, and collaboration with project teams, with regular lab leadership responsibilities in a fast‑paced discovery setting.

Qualifications

• 3+ years of direct/demonstrated experience with LC-MS in a CRO or industry lab in Bioanalytical Method Development, Drug Metabolism/Metabolite Identification, or MS‑Based Proteomics.
• Experience validating bioanalytical methods per FDA/ICH/OECD guidelines.
• Experience working in a Quality Management System.

Responsibilities

• Perform work in a laboratory setting and meet the physical job requirements of a lab role.
• Provide leadership and mentorship for junior scientists and lab leadership through daily lab management and planning.
• Develop LC-MS methods for ADME‑Tox and BioAnalysis applications and support project teams.
• Troubleshoot and maintain Mass Spectrometers and HPLC units.
• Support validation of new analytical methods and contribute to service expansion.

Skills

LC-MS expertise

Team leadership

Quality management

Regulatory knowledge

Education

BS with 3 years of relevant experience

MS with 2 years of relevant experience

PhD with 1 year of relevant experience

Tools

Sciex instruments

Thermo Scientific MS

HPLC/UPLC

Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Are you looking to grow your experience in the ADME‑Tox space? Look no further! Come join our dynamic and growing team for a great opportunity. The Scientist I will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry method development and analysis, with related experience in a contract research organization (CRO) or industry laboratory.

Here’s what you’ll do:

• Perform work in a laboratory setting and meets the physical job requirements of a lab role.
• Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
• Perform work in a laboratory setting, meeting the physical job requirements of a lab role.
• Develop Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications
• Develop analytical methods supporting project teams both internally and externally for new assay development.
• Perform Troubleshooting and Maintenance of Mass Spectrometers and HPLC units.
• Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
• Prepare and manages inventory of buffers, reagents, semi-finished and finished goods.
• Provide solutions to more complex problems, identifies and initiates process improvements
• Perform data and report QC review within the department and may support the Study Director.
• Support validation of new methods that contribute to expansion of service/product line, equipment, and data management systems.

Qualifications

The ideal candidate:

• 3+ years of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas:
  • Bioanalytical Method Development for Small and/or Large Molecules
  • Drug Metabolism and Metabolite Identification w/ Structural Elucidation
  • Mass Spectrometry-Based Proteomics experimental design & execution
• Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
• Experience working in a Quality Management System.
• Demonstrated proficiency in High-Throughput analytical method development for small molecules.
• Experience in leading and delivering results in R&D or innovation programs.
• Demonstrated experience leading in human mammalian cell culture laboratories.
• Demonstrated experience working with light-based readers with 384-well and 96-well plates.
• B.S. with 3 years of relevant experience
• M.S. with 2 years of relevant experience
• Ph.D. with 1 year of relevant experience
• Or an equivalent combination of education and experience
• Ability to work in the U.S. indefinitely without sponsorship or restriction

Additional Information

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed. Candidates living within a commutable distance of St. Charles, MO are encouraged to apply.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.