Laboratory Analyst / Analytical Chemist – LC-MS/MS & GC-MS/MS

Dope Diagnostics; Pearl River (NY); On-site; USD 45,000 - 52,000; Full time

Benefits offered by this job

On-site facility

Career growth opportunities

Job summary

Dope Diagnostics is launching a New York State cannabis testing laboratory in Pearl River, NY focused on rigorous analytical science, regulatory compliance, data integrity, and defensible laboratory results. The Laboratory Analyst / Analytical Chemist will operate LC-MS/MS, GC-MS, and GC-MS/MS with instrument tuning, method validation, troubleshooting, and data review.

The candidate will prepare samples, standards, and QC materials; review chromatograms and results; and contribute to method

Qualifications

• Bachelor's degree in a related scientific discipline or equivalent combination of education and experience.
• At least two years of practical analytical laboratory experience.
• Meaningful hands-on experience with LC-MS/MS and/or GC-MS(/MS).
• Experience preparing analytical samples, standards, QC materials.

Responsibilities

• Perform preparation and analysis of samples using LC-MS/MS, GC-MS, and GC-MS/MS methods.
• Prepare samples, calibration standards, internal standards, blanks, spikes, and QC materials.
• Operate LC-MS/MS and GC-MS/MS instrumentation for routine and non-routine testing.
• Troubleshoot analytical and instrument issues and monitor QC results.

Skills

LC-MS/MS

GC-MS

GC-MS/MS

Mass spectrometry

Quality control

Education

Bachelor's degree

Tools

LC-MS/MS instrument

GC-MS instrument

LIMS

Job description

Compensation: $33.00–$38.00 per hour, depending on experience

Dope Diagnostics is preparing to launch a New York State cannabis testing laboratory in Pearl River, New York focused on rigorous analytical science, regulatory compliance, data integrity, and defensible laboratory results.

We are seeking a Laboratory Analyst / Analytical Chemist with hands-on LC-MS/MS, GC-MS, and GC-MS/MS experience to join our analytical chemistry team.

This position is intended for a scientist who has meaningful practical experience operating mass-spectrometry instrumentation and is comfortable participating in instrument setup, calibration, method validation, troubleshooting, analytical testing, quality control, and data review.

Cannabis-testing experience is preferred but not required. Candidates from pharmaceutical, environmental, food-safety, chemical, forensic, or other regulated analytical laboratories are encouraged to apply.

Responsibilities

The Laboratory Analyst / Analytical Chemist will:

• Perform preparation and analysis of samples using LC-MS/MS, GC-MS, and GC-MS/MS methods.
• Prepare samples, calibration standards, internal standards, blanks, spikes, controls, reagents, and other analytical materials.
• Operate LC-MS/MS and GC-MS/MS instrumentation for routine and non-routine analytical testing.
• Perform instrument tuning, calibration, system-suitability testing, and performance verification.
• Monitor analytical sequences and evaluate chromatography, calibration curves, internal-standard response, QC results, and instrument performance.
• Perform routine and preventive instrument maintenance.
• Troubleshoot analytical and instrument issues involving chromatography, sensitivity, carryover, peak shape, retention time, calibration, contamination, and system performance.
• Participate directly in method development, verification, validation, transfer, and implementation.
• Execute approved validation protocols and accurately document validation results.
• Review chromatograms, quantitative results, calibration data, QC results, and supporting analytical records.
• Identify and investigate deviations, failed QC, unusual analytical results, instrument issues, and other conditions affecting data validity.
• Assist with corrective actions and document investigations as required by the laboratory quality system.
• Perform or support testing for pesticides, mycotoxins, residual solvents, terpenes, and other contaminants using assigned LC-MS/MS, GC-MS, and GC-MS/MS methods.
• Enter and review analytical information and results in LIMS.
• Maintain complete and contemporaneous instrument, maintenance, calibration, sample-preparation, analytical, and quality-control records.
• Maintain sample integrity and chain-of-custody documentation.
• Work in accordance with Dope Diagnostics' ISO/IEC 17025 quality-management system and applicable New York State Office of Cannabis Management requirements.
• Work collaboratively with laboratory leadership as the laboratory completes validation, regulatory approval, and commercial launch.

Required Qualifications

• Bachelor's degree in chemistry, analytical chemistry, biochemistry, pharmaceutical science, environmental science, forensic science, or a related scientific discipline, or another combination of education and experience satisfying applicable New York laboratory personnel requirements.
• At least two years of practical analytical laboratory experience.
• Meaningful hands-on experience with LC-MS/MS and/or GC-MS and/or GC-MS/MS.
• Experience preparing analytical samples, calibration standards, internal standards, blanks, spikes, and QC materials.
• Understanding of chromatographic separation and quantitative mass-spectrometry principles.
• Experience evaluating calibration curves, QC results, system suitability, and instrument-performance data.
• Ability to perform routine instrument maintenance and troubleshoot common analytical issues.
• Strong commitment to analytical data integrity and laboratory documentation.
• Ability to work effectively in a regulated, quality-controlled laboratory.
• Ability to work full-time on-site in Pearl River, New York.

Strongly Preferred Qualifications

Experience with the following is particularly desirable:

• Three or more years of LC-MS/MS and/or GC-MS and/or GC-MS/MS experience;
• Hands-on experience with both LC-MS/MS, GC-MS, and GC-MS/MS;
• SCIEX, Agilent, Shimadzu, Waters, or Thermo Fisher mass-spectrometry platforms;
• Triple-quadrupole mass spectrometry;
• Quantitative pesticide, residual solvents, terpenes or contaminant analysis;
• Cannabis pesticide and/or mycotoxin testing;
• Environmental, food-safety, pharmaceutical, or toxicology testing;
• Analytical method development and validation;
• Matrix-effect, recovery, accuracy, precision, linearity, LOD/LOQ, carryover, and robustness studies;
• Instrument troubleshooting and preventive maintenance;
• LIMS and chromatography/mass-spectrometry data systems;
• ISO/IEC 17025, GLP, GMP, or another regulated laboratory quality system.

Direct cannabis-testing experience is preferred but not required. We are particularly interested in candidates with strong mass-spectrometry experience who can transfer those skills into cannabis compliance testing.

The Candidate We Are Looking For

We are looking for someone who has spent meaningful time at the instrument, not simply someone who has been exposed to LC-MS/MS, GC-MS, and GC-MS/MS.

The successful candidate should be comfortable running analytical sequences, reviewing chromatographic and quantitative data, evaluating QC performance, performing calibrations and maintenance, diagnosing instrument problems, and helping establish reliable analytical methods.

Why Join Dope Diagnostics

This position provides an opportunity to:

• Join the laboratory during its validation and operational launch;
• Work directly with sophisticated LC-MS/MS, GC-MS, and GC-MS/MS and other instrumentation;
• Participate in method validation and implementation from the ground up;
• Work within an ISO/IEC 17025 quality framework;
• Develop expertise in New York's regulated cannabis-testing industry;
• Work alongside experienced analytical scientists and laboratory leadership; and
• Play a meaningful role in building the analytical chemistry capabilities of a new commercial laboratory.

Schedule

Full-time, Monday through Friday, on-site in Pearl River, New York. Some schedule flexibility may be required as validation and testing volumes increase.

Compensation

$33.00–$38.00 per hour, based on relevant laboratory experience, LC-MS/MS, GC-MS, and GC-MS/MS experience, education, and technical qualifications