Impactful Senior Scientist — Process Development

Amgen SA; Thousand Oaks (CA); On-site; USD 120,000 - 160,000; Full time

Job summary

Amgen in Thousand Oaks, CA, is seeking a Process Development Sr Scientist to design and execute bench-scale experiments for end-to-end drug substance processes, including cell culture and purification operations.

You will apply platform approaches, solve day-to-day challenges, and contribute to technology development while expanding skills in cell culture and purification within a cGMP manufacturing environment.

Qualifications

• Doctorate level or equivalent with strong background in biotech process development.
• Experience leading cell culture and purification development efforts in a GMP setting.
• Ability to design, execute, and troubleshoot bench-scale experiments for drug substance processes.

Responsibilities

• Design and execute bench-scale experiments across cell culture and purification operations.
• Apply platform approaches and problem‑solving to address drug substance challenges.
• Contribute to technology development and process improvements.
• Collaborate cross‑functionally with analytical and drug product teams to deliver robust manufacturing processes.
• Maintain cGMP compliant processes and generate technical/regulatory documentation.

Skills

Bioprocess

Cell culture

Protein chromatography

cGMP

Data analysis

Problem solving

Team collaboration

Education

Doctorate (PhD) or PharmD or MD

Master’s degree + 3 years scientific experience

Bachelor’s degree + 5 years scientific experience

Tools

Excel

Spotfire

R

Python

JMP

Job description

Amgen in Thousand Oaks, CA, is seeking a Process Development Sr Scientist to design and execute bench-scale experiments for end-to-end drug substance processes, including cell culture and purification operations.

You will apply platform approaches, solve day-to-day challenges, and contribute to technology development while expanding skills in cell culture and purification within a cGMP manufacturing environment.