Immunogenomics Scientist III: Target Discovery & Tools

Genentech; South San Francisco (CA); On-site; USD 103,400 - 192,000; Full time

Benefits offered by this job

Relocation benefits

Discretionary annual bonus

Job summary

Genentech is seeking a highly motivated Scientist 3 to advance target discovery through cutting-edge genomics and molecular engineering. You will develop models and read-outs to interrogate immune-mediated diseases, collaborating with teams across immunology, genomics, and AI/ML.

Leadership of multiple projects and a strong publication record are valued. The role emphasizes scientific innovation, rigorous experimentation, and effective communication, with relocation benefits available and a

Qualifications

• Doctorate in molecular biology, genetics, immunology, or related field.
• Deep immunology expertise with primary immune cell culture and functional assays.
• Strong molecular engineering background with CRISPR and genome editing tools.
• Experience in high-content genomics, single-cell analysis, proteomics or imaging.
• Proven ability to manage multiple projects and lead research efforts.
• Track record of publications and/or patents.
• Proficiency in flow cytometry and diverse biochemical/molecular techniques.
• A proactive problem-solver with strong communication and collaboration skills.
• Willingness to learn new experimental approaches and computational analyses.

Responsibilities

• Develop and deploy molecular engineering technologies to interrogate immune disease mechanisms.
• Create biologically relevant models and advanced read-outs for target discovery.
• Lead cross-disciplinary projects and collaborate with immunology, genomics, and AI/ML teams.
• Interpret results, design follow-up experiments, and communicate insights clearly.

Skills

Immunology

Leadership

Scientific productivity

Flow cytometry

Problem solving

Communication

Data analysis (R/Python)

Education

Doctorate (relevant field)

Tools

CRISPR (CRISPRko/CRISPRi)

Deep mutational scanning

Lineage tracing

Job description

Genentech is seeking a highly motivated Scientist 3 to advance target discovery through cutting-edge genomics and molecular engineering. You will develop models and read-outs to interrogate immune-mediated diseases, collaborating with teams across immunology, genomics, and AI/ML.

Leadership of multiple projects and a strong publication record are valued. The role emphasizes scientific innovation, rigorous experimentation, and effective communication, with relocation benefits available and a