Immuno-Oncology Research Associate – mRNA (Bench)

BioSpace; Cambridge (MA); On-site; USD 63,000 - 101,000; Full time

Benefits offered by this job

Competitive healthcare

Well-being resources

Family planning benefits

Generous PTO

Savings & investments

Location-specific perks

Job summary

Moderna in Cambridge, MA is seeking a Research Associate to join Immuno-Oncology Research, applying molecular biology and immunology to characterize mRNA products, their activity, and biomarkers in vitro and in vivo to support early preclinical work.

This bench-focused role requires teamwork across cross-functional groups, execution of in vitro and ex vivo experiments, and delivering high-quality, reproducible data to advance IND-enabling studies and translational research.

Qualifications

• Bachelor’s degree.
• Technical experience in cell transfection, long-term immune cell cultures, co-culture assays, and multi-color flow cytometry.
• Experience with protein detection methods (MSD, ELISA), assay development and troubleshooting, familiarity with qPCR and ddPCR.
• Self-motivated, flexible, and able to work in a fast-paced, team-oriented environment.

Responsibilities

• Use Moderna’s mRNA products to demonstrate expression and characterize activity of immuno-oncology therapeutic proteins in relevant in vitro and/or in vivo experimental systems
• Gain knowledge of preclinical cancer models and toxicology models
• Perform and/or support experiments and assays such as immune cell isolation, cell culture, ELISA/MSD, flow cytometry, cell-based functional and reporter assays, sample processing and analysis for pharmacokinetic and pharmacodynamic studies
• Work collaboratively within direct team, as well as with a cross-functional team of scientists
• Maintain an organized work area and electronic lab notebook
• Analyze, visualize, and summarize experimental data, including team meeting presentations

Skills

Cell transfection

Immune cell culture

Co-culture assays

Flow cytometry

Education

Bachelor’s degree

Tools

MSD

ELISA

qPCR

ddPCR

GraphPad Prism

Omiq

Job description

Moderna in Cambridge, MA is seeking a Research Associate to join Immuno-Oncology Research, applying molecular biology and immunology to characterize mRNA products, their activity, and biomarkers in vitro and in vivo to support early preclinical work.

This bench-focused role requires teamwork across cross-functional groups, execution of in vitro and ex vivo experiments, and delivering high-quality, reproducible data to advance IND-enabling studies and translational research.