Hsiao Lab - Full Specialist

UCSF Health, AG; San Francisco (CA); Presencial; USD 97.000 - 202.000; Jornada completa

Descripción de la vacante

UCSF Health seeks a Specialist with immunology experience and proficiency in mouse and human cell culture models of disease. The role develops and maintains research methods for bone and metabolic diseases, with involvement in gene therapy and gene editing (CRISPR/Cas9) in human iPSCs and mice.

The successful candidate will supervise personnel, contribute to translational research, and collaborate across the lab to advance scientific findings at UCSF.

Formación

• Terminal degree or 10+ years in the relevant specialization.
• FACS experience.
• Molecular biology techniques (Western blot, qPCR, electrophoresis, DNA/RNA isolation).
• Cytokine assessments/ELISA.
• Cellular assays of immune function.
• Tissue culture including human induced pluripotent stem cells.
• Use of mouse models (husbandry, euthanasia, tissue collection).
• Light/flourescence microscopy and immunohistochemistry.
• Supervisory experience.
• Excellent communication, organizational, and people skills.

Responsabilidades

• Develop and maintain research methodology related to bone and metabolic diseases.
• Engage in gene therapy and gene editing work, including CRISPR/Cas9 constructs in hiPSCs and mice.
• Collaborate with the lab to advance experimental approaches and project milestones.
• Supervise lab personnel and coordinate workflows.
• Contribute to scientific dissemination and reporting.

Conocimientos

FACS

Molecular biology

ELISA

Cellular assays

Tissue culture

Mouse models

Microscopy

Supervisory

Communication

Educación

Terminal degree / 10+ years experience

Herramientas

CRISPR/Cas9

qPCR

Descripción del empleo

Position description

The Hsiao Lab is seeking a Specialist. The ideal candidate should have immunology experience as well as experience using mouse and human cell culture models of human diseases. The candidate will be working with our laboratory to develop and maintain research methodology related to bone and metabolic diseases. The ideal candidate should also have experience with gene therapy and gene editing techniques, including the design and delivery of CRISPR/CAS-9 related constructs into human induced pluripotent stem cells and mice.

Required qualifications

• Must possess a terminal degree (or equivalent degree) or at least ten or more years of experience in the relevant specialization.


• FACS


• Molecular biology (westerns, qPCR, electrophoresis, DNA/RNA isolation, etc.)


• Cytokine assessments/ELISA


• Cellular assays of immune function


• Tissue culture, including human induced pluripotent stem cells


• Use of mouse models (husbandry, euthanasia, tissue collection)


• Light microscopy, fluorescence microscopy, immunohistochemistry


• Supervisory experience


• Excellent communication, organizational, and people skills

Preferred qualifications

• Experience with single cell sequencing or bulk RNAseq analysis


• MicroCT and other imaging analyses


• Experience with mouse survival surgeries


• Post-graduate training in field


• Management experience

Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary will be commensurate with the applicants experience and training.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $96,500-$201,700.

Document requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).


• Cover Letter (Optional)


• Statement of Research (Optional)


• Statement of Teaching (Optional)

Reference requirements

• 3-5 required (contact information only)

About UC San Francisco

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy

* UC Anti-Discrimination Policy

* APM - 035: Affimative Action and Nondiscrimination in Employment

Job location

San Francisco, CA