HR Operations & Program Manager

GeneFab; Alameda (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

GeneFab is seeking an HR Operations & Program Manager to own end-to-end HR systems, administer total rewards, and manage immigration and records. The role includes HRBP duties, updating policies, performance management, and coordination with Finance, IT, Internal Audit to align practices across the U.S. and Taiwan.

The candidate will develop recognition programs, oversee recruiting processes, and drive learning and development, while maintaining discretion and confidentiality.

Qualifications

• 3–6 years of progressive HR experience, including end-to-end lifecycle ownership.
• Hands-on experience administering group health and welfare benefits, open enrollment, and 401(k) coordination.
• Strong written and verbal communication skills with ability to translate policy into plain language.

Responsibilities

• Own all internal HR systems including end-to-end employee lifecycle management and HR records.
• Administer Employee Total Reward program, including core benefits, 401K, and onsite perks.
• Manage immigration and visa processing.
• Maintain and issue HR records (offer letters, templates, separation agreements).
• Own the employee handbook and policies to ensure compliance across US and Taiwan.
• Oversee performance management cycle and coordinate with Finance, IT, Internal Audit.
• Develop recognition and engagement programming and coordinate company events.
• Oversee recruiting processes and advise on recruiting best practices.

Skills

HR experience

Benefits administration

Communication skills

Recruiting support

Policy & compliance

Tools

ATS software

Job description

HR Operations & Program Manager

GeneFab Alameda, California, United States

About this position

About GeneFab

GeneFab is a contract manufacturing and synthetic biology biofoundry focused on cell and gene therapies. GeneFab was formed in 2023 with a vision to combine industry leading expertise in synthetic biology with advanced cGMP capabilities in order to accelerate the development and commercialization of genetic medicines. GeneFab offers its customers an extensive technology platform and know-how that spans early stage product design, technical development, and cGMP compliant production. GeneFab's technology platform includes bioinformatic-guided discovery of cell type promoters, directed evolution of small molecule-regulated gene switches, and the engineering of highly sensitive kill switches for enhanced safety and control of cellular therapies.

We are committed to an inclusive and diverse GeneFab. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse GeneFab team. We welcome people of different backgrounds, experiences, abilities, and perspectives and are an equal opportunity employer.

Responsibilities:

HR Operations / Generalist

• Own all internal HR systems including end to end employee lifecycle management, maintain HR records and filing systems


• Administer GeneFab's Employee Total Reward program, including core benefits, 401K, onsite perks, etc.


• Manage immigration and visa processing


• Maintain and issue all HR records (i.e. offer letters, general templates, separation agreements, etc.)

HRBP

• Own, maintain, and continuously update the employee handbook and underlying people policies to ensure State and Federal compliance.


• Own the end-to-end performance management cycle


• Partner with Finance, IT, and Internal Audit team to business operations compliant and keep people policies and practices reasonably aligned across GeneFab's U.S. and Taiwan entities.


• Oversee compliance training and Learning and Development


• Identify and drive opportunities to improve or automate HR best practices and policies as GeneFab grows


• Serve as a trusted resource for all GeneFab employees

HR Programs

• Develop recognition and engagement programming


• Coordinate Company special events


• Assess and analyze employee engagement via employee surveys


• Partner with Executive Leadership to implement employee feedback


• Create onboarding and new hire experience programming


• Oversee recruiting processes and advise on recruiting best practices


• Maintain and manage Company ATS


• Participate in Company's interviewing processes

Qualifications:

• 3–6 years of progressive HR experience, including direct, hands‑on ownership of the full employee lifecycle.


• Must be able to maintain discretion, professional integrity, and confidentiality at all times.


• Hands‑on experience administering group health and welfare benefits programs, including open enrollment, carrier/broker relationships, and 401(k) coordination.


• Ideal candidate has experience working at an early‑stage Company. Must be comfortable managing various priorities and building trust.


• Strong written and verbal communication skills — able to translate policy and process into plain language for employees and managers at every level.


• Direct experience supporting Recruiting, proficient in ATS management


• Experience in a life sciences, manufacturing, or other regulated, cGMP‑adjacent environment is strongly preferred; comfort coordinating across U.S. and international offices (e.g., Taiwan) is a plus.


• Must be able to work from GeneFab's ALM HQ on a regular and consistent basis.


• Preferred system experience: Rippling, Sequoia Consulting, Lever, Microsoft 365