HR Lead

Sensei Biotherapeutics; United States; Remote; USD 130,000 - 160,000; Full time

Benefits offered by this job

Remote work

Health, dental, and vision insurance

Generous parental leave

401k plan

Flexible time off

Equity

Job summary

Faeth Therapeutics is seeking an experienced HR Lead to own Human Resources, People Operations, compensation, benefits, compliance, and employee relations in a fully remote U.S. role. The position reports to the Chief of Staff and supports a fast-paced biotech environment.

You will lead onboarding/offboarding, compensation benchmarking, equity administration, HRIS/payroll, and leave administration while driving learning, development, and internal communications across the company.

Qualifications

• Bachelor's degree in HR or related field.
• 5+ years HR experience in biotech or life sciences.
• Strong knowledge of employment law and benefits administration.
• Experience managing compensation programs and equity administration.
• Experience administering HRIS and payroll processes.
• Ability to handle confidential information with discretion.
• Excellent interpersonal and communication skills.
• Strong project management and organizational abilities.
• Ability to operate in high-growth, entrepreneurial environment.

Responsibilities

• Lead onboarding and offboarding processes.
• Serve as primary contact for employee questions.
• Manage compensation planning, benchmarking, and equity planning.
• Oversee 401(k) program and benefits.
• Administer HRIS platforms and payroll coordination.
• Maintain HR records and ensure regulatory compliance.
• Oversee leave administration and performance reviews.
• Lead learning and development and company-wide communications.
• Organize All Hands meetings and employee events.

Skills

HR experience

Employment law

Compensation management

HRIS

Discretion

Interpersonal skills

Project management

Organizational abilities

Education

Bachelor's degree in HR/Business or related field

Tools

HRIS platforms

Payroll systems

Job description

Faeth Therapeutics is a clinical-stage oncology company listed on Nasdaq that recently raised $200M in funding. With a strong scientific foundation and a founding team that includes the discoverer of our target pathway, we are advancing PIKTOR, a multi-node PI3K/AKT/mTOR inhibitor program, toward multiple near-term milestones. We are a small, focused team where every person has direct impact — united by a shared commitment to care deeply, create boldly, and never stop learning.

The HR Lead will own all aspects of Human Resources, People Operations, Compensation, Benefits, Compliance, and Employee Relations,. This role is ideal for a proactive HR professional who thrives in a fast-paced biotech environment and enjoys building scalable processes while serving as a trusted advisor to employees and leadership.

Reports to: Chief of Staff

Location: Remote (U.S.)

Responsibilities:

• Lead all onboarding and offboarding processes to ensure a seamless employee experience.
• Serve as the primary point of contact for employee questions and support.
• Manage compensation planning, benchmarking, and market analyses.
• Own equity administration and equity planning processes.
• Manage annual compensation review cycles and salary adjustments.
• Administer employee benefits programs and manage vendor relationships.
• Manage and oversee the company’s 401(k) program, including establishment and administration of a 401(k) committee.
• Serve as system administrator for HRIS platforms and related people systems.
• Manage payroll preparation and coordinate with payroll providers.
• Maintain accurate employee records and HR data and ensure compliance with federal, state, and local employment regulations.
• Oversee leave administration, including parental, medical, and other protected leaves.
• Lead and administer the annual performance review process.
• Lead learning and development programs that support employee growth and leadership development.
• Lead company-wide communications and employee engagement activities.
• Organize and facilitate All Hands meetings, team lunches, happy hours, and company events.

Requirements:

• Bachelor's degree in Human Resources, Business Administration, or related field.
• 5+ years of progressive HR experience in biotechnology, pharmaceutical, or life sciences organizations.
• Strong knowledge of employment law, HR compliance, benefits administration, and employee relations.
• Experience managing compensation programs, benchmarking, and equity administration.
• Experience administering HRIS systems and payroll processes.
• Demonstrated ability to manage sensitive and confidential information with discretion.
• Excellent interpersonal, communication, and relationship-building skills.
• Strong project management and organizational abilities.
• Ability to operate effectively in a high-growth, entrepreneurial environment.

Preferred:

• Experience supporting venture-backed or high-growth biotech companies.
• Experience with Radford compensation surveys and benchmarking.
• Experience working with Boards of Directors and Compensation Committees.
• SHRM-CP, SHRM-SCP, PHR, or SPHR certification.
• Experience managing immigration processes and employment-related legal matters.

Compensation Range: $130,000 - $160,000 (actual compensation may vary based on experience, qualifications and location)

Working at Faeth

Benefits:

• Competitive salary and equity in a well-funded, clinical-stage biotech
• 100% remote work and flexible schedule
• Health, dental, and vision for you and your dependents
• Flexible time off
• Generous parental leave
• Traditional and Roth 401k
• Mission oriented, remote first culture

We are an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

All offers of employment are contingent upon satisfactory completion of a background check and verification of eligibility to work in the United States.