Histotechnician — Advanced Tissue Processing & Digital Slides

Personalis; Fremont (CA); On-site; USD 55,000 - 69,000; Full time

Benefits offered by this job

Shift differential

Annual bonus

Equity units

Medical benefits

401(k) match

ESPP

Job summary

Personalis in Fremont, CA is seeking a Histotechnician to process FFPE specimens for microscopic evaluation in support of molecular diagnostics tests. The role reports to the department supervisor and lab director, with responsibilities spanning sectioning, staining, coverslipping, digital slide generation, and macrodissection.

The position requires an ASCP HT/HTL, 3+ years in a high-volume histology lab, and strong attention to detail.

Qualifications

• Associate's degree in chemical/physical/biological science or completion of a NAACLS-accredited Histotechnology program.
• HT or HTL certification from ASCP.
• Minimum 3+ years experience in a high-volume histology lab performing microtomy, H&E staining and embedding.
• Experience with IHC and digital imaging is a plus, ability to read pathology reports.
• Excellent attention to detail, organization, and time management; strong communication skills.

Responsibilities

• Perform sectioning of tissue using a microtome and mounting on glass slides.
• Perform routine staining of tissue sections with automated and/or manual staining techniques.
• Perform automated and/or manual coverslipping of slides.
• Generate digital slide images for pathologist examination.
• Perform manual and automated macrodissection.
• Operate and perform instrument maintenance.
• Follow laboratory safety and quality policies in histology work.
• Maintain accurate documentation in LIMS and other records.
• Support meeting turnaround time goals with high productivity.
• Keep work areas clean and organized; report issues to supervisor promptly.

Skills

Attention to detail

Time management

Effective communication

Interpersonal skills

Reading pathology reports

Education

Associate's degree in chemical/physical/biological science

NAACLS-accredited Histotechnology program

Bachelor's degree in a laboratory science

Tools

IHC staining equipment

Digital imaging systems

Laboratory Information Management Systems (LIMS)

Job description

Personalis in Fremont, CA is seeking a Histotechnician to process FFPE specimens for microscopic evaluation in support of molecular diagnostics tests. The role reports to the department supervisor and lab director, with responsibilities spanning sectioning, staining, coverslipping, digital slide generation, and macrodissection.

The position requires an ASCP HT/HTL, 3+ years in a high-volume histology lab, and strong attention to detail.