High-Throughput Protein Purification Scientist (Automation)

Lila Sciences

Cambridge (MA)

On-site

USD 88,000 - 144,000

Full time

14 days+

Get more replies from employers

Send a job-specific resume in minutes.

Benefits offered by this job

Medical, dental, vision
Commuter benefits including bike share
Education assistance
Parental leave

Job summary

Lila Sciences is seeking an Associate Scientist/Scientist I focused on high‑throughput protein purification and analytics. You will design, optimize, and execute purification workflows using chromatography systems, develop and validate bioassays, and apply mass spectrometry to support protein characterization across Lila's autonomous laboratory platform.

You will collaborate with AI scientists, automation engineers, and cross‑functional teams to accelerate scientific workflows, ensure data

Qualifications

  • MS/PhD with 4+ years of relevant experience or PhD with 0–2 years postdoc/industry experience.
  • Proficiency with AKTA chromatography systems across affinity, SEC, HIC, and IEX.
  • Hands-on LC-MS for protein characterization and PTM analysis.
  • Experience in developing and validating bioassays (ELISA, AlphaLISA, SPR/BLI).
  • Strong data interpretation, record-keeping, and collaborative skills.

Responsibilities

  • Design and optimize high-throughput protein purification workflows.
  • Operate AKTA systems across diverse protein classes.
  • Perform mass spectrometry analyses to confirm identity and purity.
  • Develop and validate robust bioassays to assess function and quality.
  • Partner with automation teams to integrate workflows into high-throughput platforms.
  • Ensure data quality, documentation, and reproducibility across experiments.
  • Collaborate with computational scientists to support data pipelines and predictive modeling.

Skills

Protein purification
AKTA chromatography
Mass spectrometry
Bioassay development
Data analysis
Laboratory automation
Collaborative work

Education

MS in Biochemistry/Biophysics/Bioengineering/Molecular Biology or related field
PhD in related discipline

Tools

Benchling
LC-MS instrumentation

Job description

Lila Sciences is seeking an Associate Scientist/Scientist I focused on high‑throughput protein purification and analytics. You will design, optimize, and execute purification workflows using chromatography systems, develop and validate bioassays, and apply mass spectrometry to support protein characterization across Lila's autonomous laboratory platform.

You will collaborate with AI scientists, automation engineers, and cross‑functional teams to accelerate scientific workflows, ensure data

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Associate Scientist/Scientist I, Protein Science Developability
Associate Scientist/Scientist I, Protein Science Developability

Lila Sciences • Cambridge (MA)

On-site
USD 88,000 - 144,000
Medical, dental, vision
Commuter benefits including bike share
Education assistance
+1
High-Throughput Protein Expression Scientist
High-Throughput Protein Expression Scientist

Eli Lilly and Company • San Diego (CA)

On-site
USD 71,000 - 162,000
Company bonus
401(k) and benefits
Vacation benefits
Senior Scientist – Protein Sciences & Laboratory Automation
Senior Scientist – Protein Sciences & Laboratory Automation

Commonwealth Sciences, Inc. • Boston (MA)

On-site
USD 120,000 - 150,000
Autonomous Protein Purification & QC Research Associate
Autonomous Protein Purification & QC Research Associate

Medra • San Francisco (CA)

On-site
USD 65,000 - 95,000
Equity ownership
401k
Medical and dental insurance
+3
Senior Protein Scientist - Lab Automation & Biologics
Senior Protein Scientist - Lab Automation & Biologics

Commonwealth Sciences, Inc. • Boston (MA)

On-site
USD 120,000 - 150,000
Associate Engineer, Materials & Lab Automation
Associate Engineer, Materials & Lab Automation

Socket.dev • Cambridge (MA)

On-site
USD 68,000 - 101,000
Senior Purification Scientist — High-Throughput SFC/LC
Senior Purification Scientist — High-Throughput SFC/LC

Jobless • San Diego (CA), Northern (KY)

Hybrid
USD 140,000 - 160,000
Shift Supervisor, Research Operations
Shift Supervisor, Research Operations

Lila Sciences • Cambridge (MA)

On-site
USD 119,000 - 182,000
Senior Protein Scientist, Small Molecule Therapeutics
Senior Protein Scientist, Small Molecule Therapeutics

Socket.dev • Cambridge (MA)

On-site
USD 156,000 - 246,000
Associate Scientist, Antibody Sciences — High-Throughput Protein
Associate Scientist, Antibody Sciences — High-Throughput Protein

Immunome, Inc. • Bothell (WA)

On-site
USD 87,000 - 102,000