High-Throughput cDNA Display Scientist

Manifold Bio; Boston (MA); On-site; USD 85,000 - 130,000; Full time

Job summary

A biotechnology firm in Boston is seeking a scientist to build an automated cell-free display platform for screening protein binder libraries. The ideal candidate will have a PhD in a relevant field and hands-on experience with cell-free display technologies. Responsibilities include designing and scaling the platform, collaborating with teams on model training, and supporting discovery campaigns. This role is at the intersection of protein engineering, lab automation, and AI-driven drug discovery.

Qualifications

• Deep expertise in cell-free display technologies.
• Strong molecular biology fundamentals.
• Ability to develop and troubleshoot complex workflows.

Responsibilities

• Design and validate a cell-free display platform suitable for diverse binder formats.
• Collaborate with automation team to scale automated screening platform.
• Ensure screening outputs effectively feed into model training pipelines.

Education

PhD or equivalent experience in protein biochemistry, molecular biology, biological engineering, or a related field

Tools

cell-free selection systems (cDNA display, mRNA display, ribosome display)

laboratory automation

Job description

A biotechnology firm in Boston is seeking a scientist to build an automated cell-free display platform for screening protein binder libraries. The ideal candidate will have a PhD in a relevant field and hands-on experience with cell-free display technologies. Responsibilities include designing and scaling the platform, collaborating with teams on model training, and supporting discovery campaigns. This role is at the intersection of protein engineering, lab automation, and AI-driven drug discovery.