Head of AI Portfolio & Governance

BioSpace; Oxford (PA); On-site; USD 190,000 - 230,000; Full time

Job summary

Immunocore is seeking a Senior Director, AI Portfolio & Governance to lead the enterprise AI strategy through disciplined portfolio management and governance. Reporting to the CIO, you will establish processes to assess, prioritize, approve, deliver and measure AI investments across R&D, Clinical, Regulatory, Medical, Commercial and corporate functions.

The role operates across AI engineering, Enterprise Systems, Data, IT Compliance, Legal, Privacy and Security, providing the structure to move

Qualifications

• Bachelor's or advanced degree in computer science, engineering, life sciences, business or related field.
• Typically 12+ years of enterprise technology, digital transformation, portfolio or program leadership, AI/data products, governance or regulated technology delivery.
• Experience establishing or running portfolio, governance or operating processes.
• Strong working knowledge of generative AI, LLM-based applications and agentic automation.

Responsibilities

• Translate the enterprise AI strategy into a managed portfolio, operating cadence and execution plan.
• Own the AI portfolio intake process, ensuring opportunities are captured, assessed and shaped before investment.
• Run portfolio prioritization and sequencing with CIO and leadership decisions.
• Develop and maintain business cases and investment proposals for AI initiatives.
• Establish and operate the AI governance process with IT Compliance, Legal, Privacy and Security.
• Translate AI policies and controls into practical operating processes.
• Maintain the enterprise AI portfolio view and provide concise reporting to CIO and senior leadership.
• Coordinate cross-functional execution across business owners, AI engineering, Enterprise Systems, Data and partners.
• Drive adoption and value realization for deployed AI capabilities and measurable benefits.
• Support scientific and healthcare AI opportunities by structuring use cases and engaging resources.
• Manage selected strategic vendors with clear scope and governance.
• Continuously improve the AI operating model.

Skills

Portfolio management

Cross-functional leadership

Executive communication

Generative AI knowledge

Education

Bachelor's or advanced degree in CS/engineering/life sciences/business

Job description

Immunocore is seeking a Senior Director, AI Portfolio & Governance to lead the enterprise AI strategy through disciplined portfolio management and governance. Reporting to the CIO, you will establish processes to assess, prioritize, approve, deliver and measure AI investments across R&D, Clinical, Regulatory, Medical, Commercial and corporate functions.

The role operates across AI engineering, Enterprise Systems, Data, IT Compliance, Legal, Privacy and Security, providing the structure to move