GPS Continuous Improvement Manager

Biopharma Careers; King of Prussia (PA); On-site; USD 140,000 - 190,000; Full time

Job summary

GSK is seeking a GPS Continuous Improvement Manager at our King of Prussia site to lead end-to-end process improvement across safety, quality, delivery and cost. You will coach teams, deploy GPS standards, and drive measurable business impact through data analytics and structured problem solving.

This on-site role partners with manufacturing, quality, MSAT, engineering, EHS and supply chain to identify opportunities and deliver sustainable improvements.

Qualifications

• Bachelor’s degree in engineering, operations, supply chain, or related field.
• Lean/Six Sigma Green Belt certification.
• 8+ years of experience leading continuous improvement in an operating environment.
• 4+ years in regulated manufacturing (biopharma/pharma/medical device) preferred.
• 2+ years teaching and coaching continuous improvement (DMAIC or A3).
• 1+ years of strategy deployment at site or business-unit level.
• 1+ year building or strengthening a Lean management system.
• 1+ year leading cross-functional change.

Responsibilities

• Lead end-to-end continuous improvement projects using Lean and Six Sigma to improve safety, quality, delivery and cost.
• Coach and develop site teams and leaders to adopt GPS standards including standard work and structured problem solving.
• Establish and manage performance routines and metrics to track progress and report business impact.
• Use data and digital tools to turn insights into clear, timely actions at the frontline.
• Standardize and sustain improvements through processes, training and documented controls.
• Partner with stakeholders across functions to remove barriers and ensure changes are implemented and measured.

Skills

Analytical Thinking

Artificial Intelligence (AI)

Biopharmaceutical Manufacturing

Data-Driven Decision Making

Data Integrity

Digital Fluency

GxP Regulations

Influencing Without Authority

Lean Management

Problem Solving

Process Improvements

Project Management

Risk Awareness

Workshop Facilitation

Education

Bachelor’s degree in engineering, operations, supply chain, or related field

Lean/Six Sigma Green Belt certification

Tools

ERP systems

MES systems

Job description

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.

Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.

We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

As a GPS Continuous Improvement Manager, you will lead continuous improvement activities across the site to improve performance around safety, quality, delivery, cost and people pillars . You will work closely with manufacturing, quality, MSAT, engineering , EHS and supply chain team s to ide ntify opportunities, run improvement projects, and embed sustainable ways of working. We value practical problem-solving, coaching, and collaboration. This role of fers strong g rowth , visible impact on operations, and alignment with our mission of uniting scie nce, techn ology and talent to get ahead of disease together.

This role will pr ovide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Lead end-to-end continuous improvement projects using Lean and Six Sigma to improve safety, qual ity, del ivery and cost.
• Coach and develop site teams and leaders to adopt GSK Production System ( GPS ) standards including standard work, tiered performance management, and structured problem solvin g.
• Esta blish and manage performance routines and metrics to track progress and report business impact.
• Use data and digital tools to turn insights into cl ear, t imely actions at the frontline.
• Standardize and sustain improvements through processes, training, and documented controls.
• Partner with stakeholders across functions to remove barriers and ensure changes are implemented and measured.

Working pattern

This role is on-site . You will be expected to work on-site regularly to engage with frontline teams and attend meetings. Some remote work is supported to enable flexible collaboration in case by case basis.

Why You?

Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals

• Bachelor’s degree in engineering, operations, supply chain, or related field such as math , science, technology , Stem etc .
• Lean/Six Sigma Green Belt certification
• 8+ years of experience leading continuous improvement, operational excellence or production-system deployment in an operating environment .
• 4+ years of experience in regulated manufacturing such as biopharmaceutical, pharmaceutical, medical device or a comparable environment. G x P or FDA experience is preferred.
• 2+ years of experience t eaching and c oaching continuous improvement including problem solving using DMAIC or A3 metho dologies
• 1+ years of experience with strategy deployment (Hoshi n Kan ri) at site or business-unit level
• 1+ year of e xperience building or strengthening a Lean management system
• 1 + years of e xperience leading cross-functional change

Preferred Qualification

• L ine leadership experience in manufacturing or supply chain with direct accountability for operational performance.
• Lean/Six Sigma Black Belt or Master Black Belt certification.
• Experience designing and delivering capability bu ilding programs
• Experience establishing or improving an employee improvement-idea process, with evidence of participation, implementation and sustained use.
• Experience using data and analytics in improvement work and assessing where digital, automation or AI can add value.
• Proven track record delivering measurable operational improvements.
• Strong facilitation and coaching skills with the ability to influence across functions.
• Practical knowledge of ERP or MES systems and industrial analytics.
• Project management experience, including sprint planning and dependency management.
• Experience developing leaders and building capability at scale.
• Familiarity with statistical tools or process capability analysis.

Skills

Analytical Thinking, Artificial Intelligence (AI), Biopharmaceutical Manufacturing, Data-Driven Decision Making, Data Integrity, Digital Fluency, GxP Regulations, Influencing Without Authority, Lean Management, Problem Solving, Process Improvements, Project Management, Risk Awareness, Workshop Facilitation

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/