GMP IT/OT Technician – Manufacturing Systems Expert

PolyPeptide US; Torrance (CA); On-site; USD 90,000 - 110,000; Full time

Job summary

PolyPeptide US in Torrance, CA is seeking an experienced IT/OT Technician to join the Site IT team. You will ensure reliability, compliance, and lifecycle management of manufacturing IT/OT infrastructure supporting GMP operations.

You will work with Engineering, Manufacturing, Quality, Global IS/IT, and vendors to maintain validated systems, manage hardware, and support end-user computing. The role emphasizes availability, change control, cybersecurity, and continuous improvement to minimize

Qualifications

• 5+ years of relevant experience in IT/OT infrastructure, industrial IT, or technical systems support.
• Hands-on experience with hardware, Windows-based systems, network connectivity, and infrastructure lifecycle management.
• Understanding of GxP requirements, change control, documentation, and maintaining validated systems in a regulated environment.
• Knowledge of OT infrastructure, cybersecurity, system availability, and technology obsolescence.
• Strong troubleshooting, problem-solving, communication, and documentation skills.
• Ability to collaborate effectively with Engineering, Manufacturing, Quality, Global IT, and external vendors.

Responsibilities

• IT/OT Infrastructure & Connectivity: Maintain and troubleshoot manufacturing system hardware, servers, workstations, network connectivity, and equipment interfaces.
• Lifecycle Management: Manage infrastructure upgrades, hardware replacement, obsolescence planning, system inventories, and end-of-support risks.
• Availability & Reliability: Investigate infrastructure issues, perform root cause analysis, and implement improvements to minimize manufacturing downtime.
• GxP Compliance: Ensure infrastructure changes are appropriately documented and controlled, working with Engineering, Quality, and Validation to maintain the validated state of applicable systems.
• Cybersecurity & Resilience: Support access controls, patch management, backups, recovery procedures, and OT security in coordination with Global IT and Engineering.
• Site IT Support: Provide secondary support for end-user computing, hardware deployment and replacement, Windows endpoints, and other local IT services.
• Collaboration: Coordinate with system owners, vendors, and cross-functional teams to resolve issues and improve manufacturing technology support.

Skills

IT/OT infra

Windows systems

Troubleshooting

Documentation

Collaboration

Tools

SCADA

DCS

MES

Job description

PolyPeptide US in Torrance, CA is seeking an experienced IT/OT Technician to join the Site IT team. You will ensure reliability, compliance, and lifecycle management of manufacturing IT/OT infrastructure supporting GMP operations.

You will work with Engineering, Manufacturing, Quality, Global IS/IT, and vendors to maintain validated systems, manage hardware, and support end-user computing. The role emphasizes availability, change control, cybersecurity, and continuous improvement to minimize