GMP Bioconjugation Process Development Engineer II

Regeneron; Village of Tarrytown (NY); On-site; USD 110,000 - 150,000; Full time

Job summary

Regeneron seeks a Process Development Engineer II for its PMPD group in Tarrytown, NY. You will design and develop scalable GMP-ready bioconjugation and purification processes while collaborating to apply QbD principles and support tech transfer to CDMOs.

This role requires a Bachelor’s degree with 5–6 years or a Master’s with 3–4 years in chemical/biochemical engineering, experience with antibodies, bioconjugation, downstream purification, and analytical tools like HPLC, MS, and

Qualifications

• Bachelor’s degree with 5–6 years or Master’s with 3–4 years in chemical/biochemical engineering or related field.
• Experience with bioconjugation processes and downstream purification techniques.
• Experience with analytical tools: HPLC, MS, electrophoresis, UV spectroscopy.
• Familiarity with DOE and QbD in GMP settings.
• Strong communication and cross-functional collaboration.

Responsibilities

• Design and develop scalable GMP-ready bioconjugation and purification processes.
• Collaborate with analytical groups to establish analytic characterization techniques.
• Discuss plans in cross-functional teams to evaluate processes and goals.
• Proactively comply with lab safety and regulatory expectations (FDA/DoT).
• Use DOE to optimize bioconjugation, purification, and analytics.
• Transfer processes with CDMOs for GMP production with first-time success.
• Develop new technologies and predictive process models; author docs.
• Mentor junior team members and present data for decision making.

Skills

Bioconjugation

DOE

Data presentation

Education

Bachelor’s degree in chemical/biochemical engineering

Master’s degree in chemical/biochemical engineering

Tools

Chromatography

Ultrafiltration/Diafiltration

Membrane technologies

Electrophoresis

Mass spectrometry

HPLC

UV spectroscopy

Job description

Regeneron seeks a Process Development Engineer II for its PMPD group in Tarrytown, NY. You will design and develop scalable GMP-ready bioconjugation and purification processes while collaborating to apply QbD principles and support tech transfer to CDMOs.

This role requires a Bachelor’s degree with 5–6 years or a Master’s with 3–4 years in chemical/biochemical engineering, experience with antibodies, bioconjugation, downstream purification, and analytical tools like HPLC, MS, and