Global Trials Optimization Specialist - Remote PM I

Syneos Health; Connecticut; On-site; USD 81,000 - 145,000; Full time

Benefits offered by this job

company car or car allowance

Health benefits to include Medical, 2?

Company match 401k

Employee Stock Purchase Plan

commission/bonus eligibility

flexible PTO and sick time

Job summary

Syneos Health in the United States seeks a Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote) to support feasibility, recruitment planning, and in-life trial optimization across global studies.

You will translate trial goals, country inputs, and enrollment insights into practical strategies, partnering with clinical trial teams, vendors, legal, and analytics to drive enrollment success and deliver actionable reports throughout the lifecycle.

Qualifications

• Experience supporting clinical trials, feasibility, recruitment planning, enrollment strategy, or trial optimization.
• Strong ability to gather, interpret, and apply data to support planning and decision-making.
• Experience coordinating timelines, deliverables, stakeholder reviews, and cross-functional inputs.
• Ability to work with clinical trial teams, vendors, legal, analytics, and other business partners.
• Strong written communication skills, including the ability to develop clear reports, plans, updates, and study-facing materials.
• Detail-oriented approach with the ability to manage multiple priorities in a fast-paced clinical research environment.

Responsibilities

• Gather data, benchmarks, and modeling inputs to support feasibility and trial optimization planning.
• Support program review development, including content review and escalation of requirements as needed.
• Plan timelines for validation, deliverable development, stakeholder alignment, presentation preparation, and country validation requests.
• Support validation and Clinical Trials Allocation Committee activities, including scenario planning, risk table inputs, validation review, modeling updates, and final allocation requests.
• Author the initial Global Trials Optimization Report and maintain subsequent report updates throughout the trial lifecycle.
• Complete recruitment needs assessments and ensure trial-level GTO reports remain current and actionable.
• Lead early recruitment and retention planning during feasibility, including inputs for project cost estimates.
• Develop initial recruitment needs assessments and, where applicable, program-level recruitment budget estimates.
• Submit vendor requests and prepare recruitment and retention plans.
• Partner with legal on concept reviews, vendor proposal reviews, scope of work finalization, and material or tactic reviews.
• Ensure recruitment and retention plans, including enrollment support materials, are implemented effectively.
• Oversee enrollment support material development and tactic execution.
• Provide required materials to the Metrics, Analytics & Performance team to support accurate Study Optimizer plan entry.
• Request and manage appropriate system updates as trial needs evolve.
• Partner with study teams to identify enrollment challenges, assess risks, and recommend potential mitigations.
• Manage routine enrollment support materials and vendor activities.
• Monitor enrollment performance and prepare standard reporting.
• Analyze performance trends and identify opportunities for enhanced support.
• Coordinate enhanced enrollment support activities, which may include: Rescue site and country activities; Internal recruitment and retention refresher meetings; External recruitment and retention booster meetings; Additional participant- or site-facing materials; Rescue vendor engagement; Advocacy engagement and community outreach.

Skills

Clinical trials experience

Data-driven decision making

Timeline coordination

Cross-functional collaboration

Clear written communication

Job description

Syneos Health in the United States seeks a Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote) to support feasibility, recruitment planning, and in-life trial optimization across global studies.

You will translate trial goals, country inputs, and enrollment insights into practical strategies, partnering with clinical trial teams, vendors, legal, and analytics to drive enrollment success and deliver actionable reports throughout the lifecycle.