Genomics Technologist Senior - Full Time - Day Shift - Pittsburgh

American Society of Gene & Cell Therapy; Pittsburgh (Allegheny County); Hybrid; USD 90,000 - 115,000; Full time

Job summary

Allegheny Health Network is seeking a Senior Technologist to independently perform and oversee specialized testing of patient DNA, RNA, and other genetic materials.

The ideal candidate will have a Bachelor's degree in biology or clinical lab science, 5 years in a molecular diagnostics lab, and experience with NGS and qPCR. The role focuses on assay validation, quality control, and regulatory adherence (CLIA, CAP, HIPAA).

Qualifications

• Bachelor's degree in biology, chemistry, physical or clinical laboratory science.
• 5 years of experience in a Molecular Diagnostic Laboratory.
• ASCP or equivalent certification preferred.

Responsibilities

• Performs and oversees high complexity molecular testing including DNA/RNA extraction, qPCR, and NGS library prep.
• Manages operation, calibration, and troubleshooting of molecular/genomics instrumentation.
• Reviews and verifies molecular/NGS data for accuracy and regulatory compliance.
• Maintains specimen processing, reagents, inventory, and detailed documentation.
• Serves as a consultant to lab personnel and healthcare providers and participates in continuing education.

Skills

Molecular techniques

Statistical analysis

Leadership

Education

Bachelor's degree (biology/clinical lab science)

Master's in genetics/genomics

ASCP or equivalent certification

Job description

Company :

Allegheny Health Network

Job Description :

GENERAL OVERVIEW:

This job independently performs and oversees specialized testing and analysis of patient DNA, RNA, and other genetic materials to support the diagnosis, prognosis, and treatment of inherited and acquired diseases. This role involves performing complex molecular and genomic testing using advanced technologies such as next-generation sequencing (NGS), PCR, and other molecular diagnostic platforms while ensuring compliance with regulatory and quality standards

The senior technologist is responsible for overseeing specimen processing, extraction, library preparation, sequencing, quality control assessment, data review, and troubleshooting of laboratory instrumentation and assays. They work closely with laboratory staff, pathologists, and healthcare providers to ensure accurate and timely test results. Additionally, senior technologists maintain laboratory documentation, participate in assay validation and quality improvement initiatives, and adhere to CLIA, CAP, and other accreditation requirements.

ESSENTIAL RESPONSIBILITIES

• Performs and oversees the performance high complexity molecular testing including tissue preparation, DNA/RNA extraction, qPCR, NGS library prep, sequencing, and result analysis.


• Manages the operation, maintains, calibration, and troubleshooting molecular and genomics laboratory instrumentation.


• Analyze, review, and verify molecular and NGS data to ensure accuracy, quality, and regulatory compliance.


• Manage specimen processing, reagent preparation, inventory tracking, and detailed laboratory documentation.


• Serves as a consultant to laboratory personnel and other health care providers, as needed. Participates in continuing education to ensure growth and development of the laboratory.


• Communicates with manager, supervisor or co-workers concerning the needs of the laboratory including supplies for efficient laboratory operations. Assumes supervisory duties, as needed.


• Other duties as assigned or requested.

QUALIFICATIONS:

Required

• Bachelor’s degree in biology, chemical, physical or clinical laboratory science.


• 5 years of Experience in a Molecular Diagnostic Laboratory

Preferred

• Master's in Human Genetics, Genomics


• 5 years of Experience in a clinical Molecular Diagnostics Laboratory


• ASCP or Equivalent Certification

SKILLS:

• Experience with Molecular Techniques


• Statistical Analysis


• Leadership Skills

Disclaimer:

The job description has been designed to indicate the general nature and essential duties and responsibilities of work performed by employees within this job title. It may not contain a comprehensive inventory of all duties, responsibilities, and qualifications required of employees to do this job.

Compliance Requirement: This job adheres to the ethical and legal standards and behavioral expectations as set forth in the code of business conduct and company policies.

As a component of job responsibilities, employees may have access to covered information, cardholder data, or other confidential customer information that must be protected at all times. In connection with this, all employees must comply with both the Health Insurance Portability Accountability Act of 1996 (HIPAA) as described in the Notice of Privacy Practices and Privacy Policies and Procedures as well as all data security guidelines established within the Company’s Handbook of Privacy Policies and Practices and Information Security Policy.

Furthermore, it is every employee’s responsibility to comply with the company’s Code of Business Conduct. This includes but is not limited to adherence to applicable federal and state laws, rules, and regulations as well as company policies and training requirements.

Highmark Health and its affiliates prohibit discrimination against qualified individuals based on their status as protected veterans or individuals with disabilities and prohibit discrimination against all individuals based on any category protected by applicable federal, state, or local law.

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