Genomics Data Scientist Professional

Children's Hospital Colorado; Aurora (CO); Hybrid; USD 98,000 - 147,000; Full time

Benefits offered by this job

Base pay

Paid time off

Insurance

Job summary

Children's Hospital Colorado is seeking a data science professional to build and apply analytical models using large-scale genomics and patient data in the Precision Diagnostics Laboratory.

You will develop hands-on models from integrated datasets, design bioinformatics workflows for NGS analysis, and collaborate with wet and dry lab teams to produce production-ready pipelines and clear data interpretations.

Qualifications

• MS in a quantitative field (Computational Biology, Statistics, Data Science or similar).
• 3 years of data science experience in a genomics clinical lab or related setting.
• Experience with integrated clinical and genomic data is preferred.

Responsibilities

• Develop and run models on large genomics and clinical datasets.
• Prototype bioinformatics workflows for NGS analysis.
• Collaborate with engineering to productionize pipelines.
• Create visualizations and reports to communicate results.

Skills

Data science

Genomics analytics

Biostatistics

Data wrangling

Education

MS in Computational Biology

MS in Statistics

MS in Data Science

Tools

NGS analysis

Job description

Build and apply analytical models for large-scale genomics and patient data within the Precision Diagnostics Laboratory team.

Responsibilities

• Develop and run hands-on models using integrated large biological datasets, including clinical and high-dimensional, patient-level data from the Employee Health Record (EHR) to produce evidence for Precision Medicine diagnostic and therapeutic decision making.
• Partner with matrixed project teams to design and prototype bioinformatics workflows for next generation sequencing (NGS) analysis, supporting development of new assay offerings.
• Work with bioinformatics engineering team members to convert prototyped pipelines into scalable, production software.
• Analyze data to improve understanding of current methods and enable better characterization of method performance.
• Perform data wrangling, statistical analysis, and interpretation to support data-driven decisions and clearer data interpretation.
• Develop and optimize computational tools and pipelines that support scientific research and interpretation efforts.
• Create thorough documentation for development, research, and pipeline execution to maintain clarity and support compliance needs.
• Plan, execute, interpret, validate, and communicate innovative exploratory analyses to support internal decisions and development of clinical grade genomic analytical workflows.
• Produce self-service tools, detailed reports, and visualizations to communicate findings to collaborative teams.
• Protect clinical data accuracy, integrity, and security by applying best practices in data management and quality control.
• Stay current on advancements in genetic testing and data science methodologies.
• Use statistical and computational methods to analyze genetic and clinical data.
• Support early target discovery using data mining through integrative analysis of human genetic and genomic datasets.
• Collaborate with both wet- and dry-lab team members across project teams.
• Communicate key findings via interactive data visualizations and presentations.

Requirements

• Master of Science
• Master of Science degree in Computational Biology, Statistics, Data Science, or other quantitative sciences (physics, math, evolutionary biology, population genetics)
• 3 years of data science experience in a genomics clinical laboratory, genomics health tech, or applied genomics research setting
• Additional education may substitute for additional experience above the required level

Benefits

• Base pay
• Incentives
• Paid time off
• Medical/dental/vision insurance
• Company provided life and disability insurance
• Paid parental leave
• 403b employer match (retirement savings)
• Robust wellness program
• Access to professional development tools
• Education benefit to help advance your career
• Annual employee bonus programAnnual base pay increases

Shift

• Precision Diagnostics Laboratory
• Monday - Friday
• 8:00 a.m. - 5:00 p.m.
• Hybrid eligible

Salary

• Pay dependent on applicant’s relevant experience
• Annual salary range (based on 40 hours/week): $97,718.13 to $146,577.20

EEO Statement

• Equal opportunity for qualified applicants; selection based on job-related factors
• Application questions are not intended to imply illegal preferences or discrimination based on non-job-related information
• Position expected to stay open until the posted close date
• Colorado residents may redact age-identifying information (such as age, date of birth, or dates of attendance/graduation) in submitted materials