Genomics Core Associate Director – High-Throughput Sequencing

Weill Cornell Medicine; New York (NY); On-site; USD 180,000 - 210,000; Full time

Job summary

Weill Cornell Medicine is seeking an Associate Director for the Genomics Core Facility to lead high-throughput sequencing operations, oversee service lines, and drive innovation in a fast-paced, high-volume environment on the Upper East Side.

The role requires deep expertise in sequencing technologies, strategic planning, and cross-disciplinary team leadership, with a focus on quality, efficiency, and revenue growth while maintaining strict biosafety and compliance standards.

Qualifications

• PhD, MD, or equivalent doctoral degree in genomics, molecular biology, genetics, or related field.
• Minimum 8 years in high-throughput sequencing in core facility or R&D.
• Strong leadership and client-relations experience.
• Deep expertise in NGS and third-gen sequencing platforms.

Responsibilities

• Provide senior operational leadership for day-to-day activities of the Genomics Core within a high-throughput production environment.
• Partner with the Core Director to develop and implement strategic initiatives that expand services, improve performance, and strengthen institutional competitiveness.
• Ensure rigorous quality control and adherence to SOPs across DNA/RNA/Protein library preparation and sequencing workflows.
• Serve as subject matter expert in genomic, transcriptomic, epigenomic, and multi-omic technologies, including single-cell, short-read, and long-read sequencing platforms.
• Evaluate, implement, and scale emerging technologies and automation strategies to enhance efficiency, data quality, and turnaround time.
• Provide high-level consultative support to investigators on experimental design, assay selection, and methodological approaches.
• Drive a strong service culture focused on responsiveness, scientific excellence, and user satisfaction.
• Recruit, train, supervise, and mentor scientific and technical staff, fostering accountability, collaboration, and continuous improvement.
• Monitor utilization, workflow capacity, and operational metrics to support revenue growth and cost recovery targets.
• Contribute to financial oversight, including budgeting, pricing models, vendor negotiations, and service agreements.
• Ensure compliance with institutional, federal, and regulatory requirements related to biosafety, data security, and ethical research conduct.
• Build and maintain strong relationships with institutional stakeholders and external collaborators.
• Act on behalf of the Core Director as needed to maintain operational continuity.

Skills

Interpersonal skills

Team leadership

Client relationships

Sequencing technologies

Strategic thinking

Education

PhD, MD, or equivalent doctoral degree in genomics, molecular biology, genetics, or a related discipline

Tools

DNA/RNA library preparation

Sequencing platforms (short-read, long-read)

Job description

Weill Cornell Medicine is seeking an Associate Director for the Genomics Core Facility to lead high-throughput sequencing operations, oversee service lines, and drive innovation in a fast-paced, high-volume environment on the Upper East Side.

The role requires deep expertise in sequencing technologies, strategic planning, and cross-disciplinary team leadership, with a focus on quality, efficiency, and revenue growth while maintaining strict biosafety and compliance standards.