Full Stack Engineer

Worky; San Diego (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Nucleus Biologics is seeking a Full Stack Engineer in San Diego to help develop and maintain software tools used by scientists and manufacturing teams. You will join a fast-paced environment, collaborate with Marketing, Business Development, and Digital Strategy, and contribute to scalable web services.

The role emphasizes Python (FastAPI/Django/Flask), React/TypeScript, PostgreSQL, and hands-on AWS with EC2/RDS/S3, plus DevOps and strong documentation practices.

Qualifications

• BS in Computer Science, Electrical Engineering, Bioengineering, or related field.
• 0-3 years experience in a related field
• Comfortable working in fast paced environments and being self-directed. Strong leadership skills a plus.
• Strong Python, with production experience in FastAPI, Django, or Flask, and SQLAlchemy or comparable ORM depth
• Strong React and TypeScript, including modern data-fetching patterns (React Query or equivalent) and component library work
• Solid PostgreSQL: schema design, migrations, indexing, and diagnosing slow queries
• Practical DevOps: Docker, Linux server administration, Nginx, and hands-on AWS experience with EC2, RDS, and S3
• Ability to work safely in a large codebase by adhering to a strong set of processes and principles

Responsibilities

• Maintain and develop software tools used by scientists building therapies and by manufacturing teams.
• Maintain EC2 host deployments, container lifecycle, Nginx, TLS renewal, and log management.
• Manage RDS backups, restores, connectivity, query performance, and Alembic migrations.
• Monitor and repair ERP/QMS sync jobs; resolve issues for staff and customers.
• Maintain external integrations & APIs; ensure proper technical documentation.
• Collaborate with teams across Marketing, BD, and Digital Strategy to deliver tooling.

Skills

Python

React

TypeScript

SQLAlchemy

PostgreSQL

DevOps

AWS

Communication

Independent judgment

Education

Bachelor's degree in Computer Science, Electrical Engineering, Bioengineering or related field

Tools

Docker

Nginx

AWS

EC2

RDS

S3

Job description

About the role

As the Full Stack Engineer at Nucleus Biologics™, you will assist the Marketing team and report into the Business Development and Digital Strategy Manager. This individual will sit at our San Diego location.

What you'll do

You will be responsible for development & maintenance of new software tools used by scientists building therapies and by the teams manufacturing for them.

Responsibilities May Include:

• Maintenance of EC2 host: deployments, container lifecycle, Nginx, TLS renewal, disk and log management
• Maintenance of RDS instance: backups, restores, connection health, query performance, and Alembic schema migrations
• Monitor and repair scheduled ERP/QMS sync jobs
• Resolution of issues reported by internal staff and customers
• Maintenance of external integrations & API’s
• Maintain proper technical documentation

Qualifications

REQUIREMENTS:

EDUCATION:

• BS in Computer Science, Electrical Engineering, Bioengineering, or related field.

• 0-3 years experience in a related field

REQUIRED EXPERIENCE:

• Comfortable working in fast paced environments and being self-directed. Strong leadership skills a plus.
• Strong Python, with production experience in FastAPI, Django, or Flask, and SQLAlchemy or comparable ORM depth
• Strong React and TypeScript, including modern data-fetching patterns (React Query or equivalent) and component library work
• Solid PostgreSQL: schema design, migrations, indexing, and diagnosing slow queries
• Practical DevOps: Docker, Linux server administration, Nginx, and hands‑on AWS experience with EC2, RDS, and S3
• Ability to work safely in a large codebase by adhering to a strong set of processes and principles

Nice to Have:

• Experience integrating with ERP or MES systems
• Experience building out CI/CD pipelines through GitHub
• Production experience with LLM APIs, including cost control, fallback handling, and prompt‑injection defense
• Familiarity defining and standardizing systems with infrastructure-as-code (Terraform, CloudFormation)
• Experience introducing and expanding observability features (error tracking, metrics, structured logging)
• Prior experience working in cGMP environment is a plus.

SKILLS & ABILITIES:

• Strong attention to detail and organizational skills.
• Effective verbal and written communication skills
• Ability to exercise independent judgment consistent with Company guidelines
• Strong process mindset

PHYSICAL REQUIREMENTS:

• Ability to hear and speak to employees and external associates on the phone and in person.
• Ability to see the letters and numbers on a personal computer screen and on memos, reports and other documents (near vision)
• Ability to walk and/or drive between buildings on campus, up to .3 miles for San Diego based positions
• Ability to lift at 25 lbs. to a height of 3-4 feet on a regular basis.

TRAVEL REQUIREMENTS:

• May require travel to and from Nucleus Biologics offices or customer/vendor locations based on position.

NOTE: The above statements are intended to describe the general nature and level of work being performed by incumbents. They are not intended to be an exhaustive list of all responsibilities, duties and skills required by all incumbents. Incumbents may perform other duties as assigned. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Managementretainsthe right to add to or change the duties of the position at any time.