FL114 | Cambridge, MA FL114: Senior Research Associate, Genomics

Pioneering Medicines; Cambridge (MA); In loco; USD 81.000 - 107.000; Tempo pieno

Vantaggi offerti da questo lavoro

Healthcare coverage

Annual incentive program

Retirement benefits

Descrizione del lavoro

FL114, Inc. is seeking a Senior Research Associate to join our Genomics team.

We’re looking for an NGS-focused molecular biologist to support epigenetic editing programs from discovery through preclinical development, collaborating across a close-knit team of experimental and computational scientists. The role requires hands-on NGS experience and a passion for bringing novel medicines to patients in a dynamic, entrepreneurial environment.

Competenze

• 2+ years of hands-on NGS library prep experience.
• Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell.
• Direct experience operating Illumina instruments.

Mansioni

• Execution of NGS-based functional genomics assays in a high-throughput production environment addressing core R&D needs in cell state mapping and therapeutic molecular validation.
• Collaborate with research teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies.
• Contribute to the development and execution of specialized molecular assays.

Conoscenze

NGS library prep

Illumina instruments

ATAC-seq

RNA-seq

ChIP-seq

Methyl-Seq

10X Genomics

KingFisher automation

Qubit

TapeStation

BioAnalyzer

PCR/qPCR

Nucleic acid extraction

Restriction digestion/ligation

Industrial drug development

Immunology experience

Strumenti

Illumina sequencers

KingFisher

Qubit

TapeStation

BioAnalyzer

Descrizione del lavoro

FL114: Senior Research Associate, Genomics

Cambridge, MA USA

About FL114

FL114 is an innovative, privately held biotechnology company developing our novel epigenetic editing platform to treat a variety of diseases through precise, tunable modification of gene expression. FL114 was founded by Flagship Pioneering, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created. With a strong emphasis on innovation and experimental execution, FL114 cultivates a highly dynamic and entrepreneurial environment.

About the Role:

FL114, Inc. is seeking an outstanding Senior Research Associate to join our Genomics team. We’re looking for a skilled, NGS-focused molecular biologist to assist in the development and advancement of our epigenetic editing programs, from early discovery research to preclinical development and beyond. The successful candidate will be an essential member of a close-knit team of experimental and computational scientists. We are looking for enthusiastic, detail oriented, adaptive, and highly motivated individuals with a passion for bringing novel medicines to patients. Applicants should be comfortable working on a fast-paced, cross-functional scientific team.

Key Responsibilities:

• Execution of NGS-based functional genomics assays in a high-throughput production environment that address core R&D needs in cell state mapping and therapeutic molecular validation
• Collaborate with research teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies
• Contribute to the development and execution of specialized molecular assays

Required Skills:

• 2+ years of hands-on experience performing NGS library prep for Illumina platforms
  • Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell
  • Direct experience operating Illumina instruments
• Familiarity with liquid handlers and Kingfisher automation
• Proficiency with quantification/QC platforms (Qubit, TapeStation/BioAnalyzer)
• Hands-on experience with core molecular biology techniques such as nucleic acid extraction/purification, PCR/qPCR, restriction digestion/ligation
• Comfortable troubleshooting and optimizing assays/protocols
• Experience in an industrial, drug-development environment preferred
• Experience in immunological indications preferred

About Flagship

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that islargely withoutprecedent. Our team of scientists, entrepreneurial leaders, and professional capital managersare eachaligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people andplanet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in manyforms,skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL114 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL114's good faith estimate as of the date of publication and may be modified in the future.