External Manufacturing Operations Director

Immunome, Inc.; Bothell (WA); On-site; USD 200,000 - 295,000; Full time

Job summary

Immunome, Inc. in Bothell, WA, is seeking a Director/Senior Director for External Manufacturing Operations to lead Immunome’s external manufacturing network, oversee CDMOs, and partner with Technical Operations to meet clinical and commercial supply goals.

This role develops supplier governance, drives strategic relationships, supports regulatory inspections, and advances manufacturing strategies as the portfolio grows.

Qualifications

• Bachelor’s degree in biotechnology, biology, chemistry, chemical engineering, pharmaceutical sciences, or a related field; advanced degree preferred.
• Minimum of 15 years of progressive experience in the biotechnology or pharmaceutical industry, including significant responsibility for cGMP manufacturing operations and oversight of external manufacturing partners.
• Proven ability to build and manage strategic relationships with CDMOs, including engagement with senior business leaders, site heads, and executive management.
• Experience contributing to manufacturing network strategy, supply planning, technology transfer, commercial readiness, and risk management.
• Position requires domestic and international travel of up to approximately 25%, with occasional evening and/or weekend commitments based on manufacturing activities and business needs.

Responsibilities

• Provide overall leadership for Immunome’s External Manufacturing Operations function, with responsibility for the performance, development, and effectiveness of the team overseeing CDMOs and other external service providers.
• Lead, coach, and develop a team of external manufacturing professionals. Establish clear priorities, expectations, and accountabilities; support staff development and the continued growth of organizational capabilities as the portfolio and manufacturing network expand.
• Ensure Virtual Management Teams (VMTs) are empowered and operate effectively, collaboratively, and consistently across programs. Provide leadership in resolving significant risks, delays, and competing priorities that could affect supply or key program milestones.
• Establish and maintain effective governance across the external manufacturing network. Ensure business reviews, steering committees, and executive-level meetings are conducted at appropriate frequencies and with the right level of engagement. Serve as a senior escalation point for significant operational, contractual, supply, and relationship matters.
• Develop strong cross-functional relationships internally, partnering closely with Technical Operations leadership, Legal, Finance, Regulatory, and other key stakeholders to align activities and ensure business objectives are met.
• Provide senior leadership with clear and timely updates regarding manufacturing performance, supply risks, network capacity, financial considerations, and other matters requiring management attention or decision-making.
• Contribute to the development and execution of Immunome’s external manufacturing and supply network strategy, and business continuity planning.
• Support regulatory submission activities and regulatory inspections, as required .
• Contribute to the continuous improvement of Technical Operations processes, governance frameworks, and ways of working to support the continued growth of Immunome’s product portfolio and external manufacturing network.

Skills

Leadership

Strategic thinking

CDMOs

Risk management

Communication

Education

Bachelor’s degree in biotechnology, biology, chemistry, chemical engineering, pharmaceutical sciences, or related field

Job description

Immunome, Inc. in Bothell, WA, is seeking a Director/Senior Director for External Manufacturing Operations to lead Immunome’s external manufacturing network, oversee CDMOs, and partner with Technical Operations to meet clinical and commercial supply goals.

This role develops supplier governance, drives strategic relationships, supports regulatory inspections, and advances manufacturing strategies as the portfolio grows.