Exosome Purification Process Scientist

Xsome Biotech, Inc.; Raleigh (NC); On-site; USD 90,000 - 130,000; Full time

Job summary

Xsome Biotech in Raleigh, NC is seeking an Downstream Development Scientist to develop robust purification processes for particle production and to manage experiments end-to-end. You will advance downstream steps including clarification, chromatography, and TFF, and collaborate across teams to meet program milestones.

The role emphasizes independent design of experiments, critical data interpretation, and technical reporting to support scale-up, transfer, and optimization efforts in a fast-paced

Qualifications

• MS in a scientific field; advanced degree preferred.
• 2+ years in design, optimization, scale-up or troubleshooting of purification processes.
• Hands-on filtration experience (depth, UF/TF, etc.).
• Strong experience with AKTA systems and Unicorn software.

Responsibilities

• Develop robust, high-yielding purification processes for particle production.
• Design and manage experiments independently and document results.
• Support downstream development across clarification, chromatography, and TFF.
• Prepare technical reports with interpretations and recommendations.
• Lead tech transfer and risk assessments aligned with milestones.

Skills

Experiment design

Cross-functional collaboration

Process development

Education

MS degree in science

Tools

AKTA purification systems

Unicorn software

Chromatography (AEX, CEX, affinity, HIC, MMC, SEC)

Job description

Xsome Biotech in Raleigh, NC is seeking an Downstream Development Scientist to develop robust purification processes for particle production and to manage experiments end-to-end. You will advance downstream steps including clarification, chromatography, and TFF, and collaborate across teams to meet program milestones.

The role emphasizes independent design of experiments, critical data interpretation, and technical reporting to support scale-up, transfer, and optimization efforts in a fast-paced