Executive Medical Director Clinical Research - Hepatology

GSK; Collegeville (PA); On-site; USD 120,000 - 180,000; Full time

Job summary

An established industry player is seeking a dynamic Executive Director for Clinical Research in Hepatology. This pivotal role involves leading clinical trials, ensuring regulatory compliance, and collaborating with cross-functional teams to drive innovative research. The successful candidate will provide strategic oversight, mentor clinical professionals, and represent the organization at scientific forums. Join a forward-thinking company that is committed to advancing health through science and technology, and make a significant impact in the field of hepatology. If you are passionate about clinical research and leadership, this opportunity is perfect for you.

Qualifications

• Medical degree with board certification in gastroenterology or hepatology required.
• Significant experience in clinical research and managing clinical trials.

Responsibilities

• Lead the design and management of clinical trials in hepatology.
• Collaborate with cross-functional teams for cohesive clinical development.

Skills

Clinical Research

Leadership

Regulatory Affairs

Data Analysis

Risk Management

Education

Medical Degree

Board Certification in Gastroenterology/Hepatology

PhD/Pharm D/MPH

Job description

Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage, UK – London – New Oxford Street, USA - Massachusetts - Waltham
Posted Date: Mar 7 2025

GSK is seeking a dynamic and experienced Executive Director Clinical Research for Hepatology Clinical Trials to lead our clinical development programs within the hepatology therapeutic area. This role will involve strategic oversight, leadership, and management of clinical trials, ensuring scientific integrity and adherence to regulatory requirements. This position reports to the VP Clinical Research Head, Hepatology- Clinical Research and Early Programs in the Respiratory, Immunology & Inflammation Research Unit (RIIRU).

This career opportunity requires an on-site office presence (minimum of two days a week) in one of GSK’s UK (London - New Oxford Street or Stevenage) or US(PA or MA) sites.

About RIIRU:

The Respiratory, Immunology & Inflammation Research Unit was formed to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The biology unit within RIIRU (aka RIIBU) works across multiple therapy areas including neurodegenerative, immune, and metabolic disease. Neurodegenerative disease portfolio includes projects in Alzheimer’s, Parkinson’s, and ALS. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform up to Phase 2 studies in clinic. This goal is enabled through strategic external (23andMe, UK Biobank, FinnGen, Laboratory of Genomic Research, Public-Private Consortia like Accelerated Medicines Partnership, GSK-Oxford University joint Institute for Molecular and Computational Medicine, Biotech partnerships – Alector, Vesalius, Muna Therapeutics) and GSK-internal partnerships (Research Technologies).

Key Responsibilities:

• Provide strategic leadership and direction for the design, execution, and management of clinical trials in hepatology.
• Oversee the development and implementation of clinical trial protocols, ensuring alignment with regulatory requirements and GSK’s scientific standards.
• Collaborate with cross-functional teams, including research, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive clinical development plans.
• Serve as the primary point of contact for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators.
• Ensure the integrity, safety, and efficacy of clinical trials through rigorous monitoring, data analysis, and risk management.
• Lead and mentor clinical professionals, fostering a culture of innovation, collaboration, and excellence.
• Manage senior clinical scientists and physician scientists (direct reports) working on hepatology assets.
• Stay abreast of advancements in hepatology research, clinical trial methodologies, and regulatory changes to maintain GSK’s competitive edge.
• Contribute to above asset hepatology strategy.
• Assist in clinical evaluation of business development opportunities.
• Represent GSK in scientific meetings, conferences, and industry forums to advance our hepatology clinical research initiatives.

Basic Qualifications:

• Medical degree with board certification/eligibility or registration qualifications in gastroenterology/hepatology or endocrinology
• Significant experience in the pharmaceutical/biotechnology industry and clinical academic medicine in the field of hepatology.
• Significant experience in clinical research and development, with a focus on hepatology
• Regulatory experience to support product registration and GCP principles
• Experience successfully leading and managing clinical trials.
• Experience with regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

• Experience (minimum 5 years) working with global regulatory agencies and managing global clinical trials in hepatology.
• Leadership/People Management experience in clinical practice, academia and/or industry.
• PhD, Pharm D and/or MPH in addition to medical degree.
• Robust knowledge of hepatology-specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.

• Leadership of a global clinical development program in the biopharmaceutical industry.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or [phone] (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.