Executive Medical Director, Clinical Development - Berkeley, CA

Evolving Solution Services; Berkeley, Northern (CA, KY); Hybrid; USD 375,000 - 425,000; Full time

Benefits offered by this job

Bonus program

Equity awards

Benefits package

Job summary

Ray Therapeutics seeks an Executive Medical Director, Clinical Development in Berkeley, CA. You will provide strategic medical leadership for a portfolio of clinical assets, shape development strategy, and lead protocol design across trial stages in a hybrid work setting.

The ideal candidate has MD/DO, 7–10 years in biotech or pharma, deep ophthalmology or neuroscience expertise, and proven cross-functional leadership to drive regulatory submissions and pivotal studies.

Qualifications

• MD, DO, or equivalent required; ophthalmology, retina or neuroscience experience preferred.
• 7–10 years in biotech/pharma or drug development with leadership.
• Experience advancing programs and regulatory submissions is strongly preferred.
• Deep ophthalmology/neuroscience expertise related to retinal disease.
• Strong clinical trial design, GCP, safety reporting and regulatory knowledge.
• Proven ability to lead cross-functional teams and influence senior stakeholders.
• Hybrid work schedule requiring 3 days per week in the office.

Responsibilities

• Provide medical leadership for a portfolio of clinical development assets.
• Shape development strategy, lead protocol design and data interpretation.
• Represent company with investigators, regulators and partners.
• Oversee safety monitoring, endpoint strategy, and benefit-risk assessment.
• Mentor clinical team members and foster patient-centered culture.

Skills

Cross-functional leadership

Clinical trial design

Regulatory submissions

Ophthalmology/Neuroscience

Leadership experience

GCP & safety reporting

Education

MD/DO or equivalent

Job description

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Executive Medical Director, Clinical Development - Berkeley, CA

Full Time Professional Berkeley, CA, US

8 days ago Requisition ID: 1016

Salary Range: $375,000.00 To $425,000.00 Annually

About Ray Therapeutics

Ray Therapeutics mission is to restore vision to people with retinal degenerations. RayTx is using a novel bioengineered optogenetic protein optimized for human vision delivered by AAV to restore visual function in a mutation agnostic approach and without the need for light enhancing eyewear. The company is developing its lead candidate RTx-015 in retinitis pigmentosa, a degenerative retinal disease with significant unmet medical need as well as a pipeline to treat both rare and large market indications.

Executive Medical Director, Clinical Development, Berkeley, CA , Hybrid

Reporting into the CMO, the Executive Medical Director, Clinical Development will provide strategic and operational medical leadership for a portfolio of early- and/or later-stage clinical development franchise assets. This role will shape clinical development strategy, lead protocol and study execution, interpret emerging data, and represent the company with investigators, regulators, partners, and the scientific community.

The ideal candidate is a physician with deep therapeutic-area related expertise, strong drug-development experience, and the ability to translate scientific opportunities into differentiated clinical programs.

Formula for Success: Serving as a Subject Matter Expert and Project Team Leader, providing clinical oversight and medical monitoring of clinical trials, you will…

• Capitalize on your strong clinical judgment, scientific rigor, and problem-solving skills establishing a clear, differentiated clinical strategy; advance high-quality studies; build trusted relationships with external experts and regulators; and strengthen the organization’s ability to make timely, rigorous, patient-focused development decisions.
• Leverage your cross functional team leadership experience, and demonstrated ability to contribute to study design, study conduct, and emerging data interpretation as you significantly contribute to the design and execution of clinical studies, driving forward projects through clinical trials and CMC.
• Design and oversee clinical development plans, protocols, informed-consent documents, investigator brochures, and clinical study reports.
• Provide medical oversight for clinical trials, including eligibility criteria, safety monitoring, data review, endpoint strategy, and benefit-risk assessment.
• Partner closely with Clinical Operations, Regulatory Affairs, Drug Safety, Commercial, and Program Management and other functions to deliver high-quality studies on time and within budget.
• Interpret and communicate clinical, safety, biomarker, imaging, and efficacy data to support evidence-based development decisions.
• Build relationships with key opinion leaders, investigators, advisory boards, patient advocacy groups, and external collaborators.
• Support regulatory interactions, including briefing documents, agency meetings, responses to information requests, and preparation for health-authority inspections.
• Contribute to scientific communications, including abstracts, presentations, and meetings.
• Mentor and develop clinical team members and foster an accountable, patient-centered, collaborative culture.

Qualifications

• MD, DO, or equivalent required; experience in Ophthalmology, Retina, Neuroscience, or related specialty is preferred
• 7-10 years of relevant biotechnology, pharmaceutical, or drug-development experience, including substantial industry clinical-development leadership.
• Demonstrated experience advancing programs across clinical phases; experience with registrational studies and regulatory submissions strongly preferred.
• Deep expertise in ophthalmology and/or neuroscience, ideally including retinal disease, neuro-ophthalmology, or related therapeutic areas.
• Strong understanding of clinical trial design, GCP, safety reporting, biostatistics, and regulatory expectations.
• Proven ability to lead cross-functional teams and influence senior stakeholders in a fast-moving biotech environment.
• Ability to work a hybrid schedule requiring 3 days per week in the office.

Compensation Range and Benefits: For this role, the anticipated base salary range is $375,000 - $425,000 based on the candidate's professional experience level. The final salary offered for this position may take into account a number of factors including, but not limited to skills, education, and experience. Ray Therapeutics also offers annual performance-based bonus, annual equity awards and a comprehensive benefits package.

At Ray Therapeutics, we celebrate diversity and are committed to creating an inclusive environment for all employees; providing an environment of mutual respect where equal employment opportunities are available to all applicants and teammates without regard to race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law.

All employment is decided on the basis of qualifications, merit, and business need.

Search Firm Representatives Please Read Carefully

Ray Therapeutics does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Please, no phone calls or emails.