Executive Life Cycle Management Director

Neurocrine Biosciences; San Diego (CA); On-site; USD 227,000 - 398,000; Full time

Benefits offered by this job

Retirement savings plan

Paid vacation

Holidays and personal days

Parental leave

Health benefits

Job summary

Neurocrine Biosciences seeks a strategic leader to own the lifecycle management for launched brands, integrating Commercial, Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, HEOR, and Real-World Evidence.

You will partner with Commercial and Medical Affairs to align annual brand plans with multi-year lifecycle strategy, translate insights into priorities, and drive cross-functional execution.

Responsibilities

• Leads the development, alignment, and ongoing evolution of the integrated lifecycle strategy and long-range plan for launched and near-launch brands
• Serves as the senior matrix leader for the cross-functional Lifecycle Team, establishing the team’s vision, strategic context, priorities, decision framework, operating model, and measures of success
• Creates shared ownership of the total product strategy across functions while maintaining clarity regarding functional roles, responsibilities, deliverables, and decision rights
• Partners closely with Commercial and Medical Affairs leadership to connect annual brand and medical plans with the broader, multi-year lifecycle strategy
• Ensures lifecycle decisions incorporate relevant patient, caregiver, healthcare professional, payer, scientific, clinical, regulatory, competitive, market, operational, and financial insights.
• Identifies, evaluates, and prioritizes opportunities to maximize patient benefit and sustainable product value, which may include: New indications or patient populations, Label expansion opportunities, New formulations, dosing approaches, routes of administration, or delivery systems, Clinical, medical, health economic, and real-world evidence generation, Product differentiation and competitive response strategies, Market access and reimbursement opportunities, Patient identification, treatment initiation, adherence, or persistence initiatives
• Leads development of an integrated evidence strategy across Clinical Development, Medical Affairs, HEOR, Real-World Evidence, Market Access, and Commercial to address the evolving needs of patients, healthcare professionals, payers, health systems, and other stakeholders
• Brings commercial and medical perspectives into relevant clinical development, regulatory, evidence-generation, and product-development decisions while ensuring that activities remain consistent with applicable legal, regulatory, and compliance requirements
• Partners with Commercial Analytics, Forecasting, Finance, and functional leaders to develop business cases, evaluate strategic options, test key assumptions, assess value and risk, and recommend investment priorities
• Translates the lifecycle strategy into an actionable roadmap with clearly defined objectives, milestones, deliverables, dependencies, resource requirements, budgets, risks, and performance measures
• Monitors brand performance, the treatment landscape, competitor activity, scientific developments, stakeholder needs, policy changes, and other external factors that may affect the lifecycle strategy
• Maintains accountability for the quality, timeliness, and strategic coherence of integrated lifecycle recommendations and cross-functional deliverables
• Establishes effective governance, communication, and escalation pathways to ensure that material opportunities, risks, decisions, and changes are visible to appropriate senior leaders
• Communicates the lifecycle vision, priorities, progress, risks, and decisions clearly across functions and organizational levels, including executive leadership
• Anticipates and addresses misalignment, unclear ownership, competing priorities, and team performance challenges before they affect program delivery
• May lead, coach, and develop employees, contractors, program leaders, or project teams depending on organizational design
• Partners with functional leaders to assess resource and capability requirements and to ensure that appropriate expertise is engaged at the right time based on the needs and maturity of the program
• Influences without direct authority and develops trusted relationships across Commercial, Medical Affairs, Development, Regulatory, Market Access, Technical Operations, Finance, and other enterprise functions
• Focuses the team on the highest-impact activities and balances inclusive cross-functional input with decisive leadership and timely decision-making
• Leads the team in evaluating complex issues, developing scenarios, identifying strategic trade-offs, and preparing decision-ready recommendations for portfolio, executive, and other governance forums
• Ensures lifecycle planning and related activities are conducted in accordance with applicable laws, regulations, industry standards, and company policies and procedures
• Performs other duties as assigned

Job description

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)

About the Role:

Provides strategic leadership for the lifecycle management of assigned commercial-stage and near-launch products, with a primary emphasis on maximizing the long term patient and business value of launched brands. Leads the development and advancement of an integrated, multi-year lifecycle strategy that connects Commercial, Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, Health Economics and Outcomes Research, and other relevant functions. Establishes the strategic context, creates shared ownership of the total lifecycle plan, and ensures that cross-functional perspectives are translated into clear priorities, investment choices, and coordinated execution. Works particularly closely with Commercial and Medical Affairs leadership to ensure that market, patient, healthcare professional, payer, scientific, clinical, and competitive insights are foundational to lifecycle decisions.

Your Contributions

• Leads the development, alignment, and ongoing evolution of the integrated lifecycle strategy and long-range plan for assigned launched and near-launch brands
• Serves as the senior matrix leader for the cross-functional Lifecycle Team, establishing the team’s vision, strategic context, priorities, decision framework, operating model, and measures of success
• Creates shared ownership of the total product strategy across functions while maintaining clarity regarding functional roles, responsibilities, deliverables, and decision rights
• Partners closely with Commercial and Medical Affairs leadership to connect annual brand and medical plans with the broader, multi-year lifecycle strategy
• Ensures lifecycle decisions incorporate relevant patient, caregiver, healthcare professional, payer, scientific, clinical, regulatory, competitive, market, operational, and financial insights.
• Identifies, evaluates, and prioritizes opportunities to maximize patient benefit and sustainable product value, which may include: New indications or patient populations, Label expansion opportunities, New formulations, dosing approaches, routes of administration, or delivery systems, Clinical, medical, health economic, and real-world evidence generation, Product differentiation and competitive response strategies, Market access and reimbursement opportunities, Patient identification, treatment initiation, adherence, or persistence initiatives, Geographic expansion, strategic partnerships, or external innovation opportunities
• Leads development of an integrated evidence strategy across Clinical Development, Medical Affairs, HEOR, Real-World Evidence, Market Access, and Commercial to address the evolving needs of patients, healthcare professionals, payers, health systems, and other stakeholders
• Brings commercial and medical perspectives into relevant clinical development, regulatory, evidence-generation, and product-development decisions while ensuring that activities remain consistent with applicable legal, regulatory, and compliance requirements
• Partners with Commercial Analytics, Forecasting, Finance, and functional leaders to develop business cases, evaluate strategic options, test key assumptions, assess value and risk, and recommend investment priorities
• Translates the lifecycle strategy into an actionable roadmap with clearly defined objectives, milestones, deliverables, dependencies, resource requirements, budgets, risks, and performance measures
• Monitors brand performance, the treatment landscape, competitor activity, scientific developments, stakeholder needs, policy changes, and other external factors that may affect the lifecycle strategy
• Maintains accountability for the quality, timeliness, and strategic coherence of integrated lifecycle recommendations and cross-functional deliverables
• Establishes effective governance, communication, and escalation pathways to ensure that material opportunities, risks, decisions, and changes are visible to appropriate senior leaders
• Communicates the lifecycle vision, priorities, progress, risks, and decisions clearly across functions and organizational levels, including executive leadership
• Anticipates and addresses misalignment, unclear ownership, competing priorities, and team performance challenges before they affect program delivery
• May lead, coach, and develop employees, contractors, program leaders, or project teams depending on organizational design
• Partners with functional leaders to assess resource and capability requirements and to ensure that appropriate expertise is engaged at the right time based on the needs and maturity of the program
• Influences without direct authority and develops trusted relationships across Commercial, Medical Affairs, Development, Regulatory, Market Access, Technical Operations, Finance, and other enterprise functions
• Focuses the team on the highest-impact activities and balances inclusive cross-functional input with decisive leadership and timely decision-making
• Leads the team in evaluating complex issues, developing scenarios, identifying strategic trade-offs, and preparing decision-ready recommendations for portfolio, executive, and other governance forums
• Ensures lifecycle planning and related activities are conducted in accordance with applicable laws, regulations, industry standards, and company policies and procedures
• Performs other duties as assigned

Requirements

BS or BA degree AND 16+ years of biotechnology or pharmaceutical experience: Significant experience in commercial strategy, brand leadership, new-product planning, portfolio strategy, product development, or lifecycle management within the biotechnology or pharmaceutical industry OR MA degree or MBA AND 14+ years of biotechnology or pharmaceutical experience OR PharmD, PhD, MD AND 12+ years of biotechnology or pharmaceutical experience Demonstrated experience with post-launch lifecycle planning, including identifying and advancing opportunities to sustain growth, strengthen differentiation, expand the evidence base, address evolving stakeholder needs, or extend product value Experience contributing to or leading a pharmaceutical product launch and subsequent post-launch strategy is strongly preferred Demonstrated ability to lead complex, multidisciplinary teams in a matrixed organization and deliver results through influence rather than direct authority Strong understanding of pharmaceutical commercialization, including brand strategy, market development, forecasting, competitive strategy, market access, evidence needs, and performance measurement Demonstrated experience partnering closely with Medical Affairs and an understanding of medical strategy, evidence generation, scientific communications, field medical, HEOR, and real-world evidence Broad understanding of the drug-development and commercialization process, including Clinical Development, Regulatory Affairs, product development, manufacturing and supply, launch readiness, and post-approval lifecycle management Strong commercial and financial acumen, including experience evaluating business opportunities, investment requirements, forecast assumptions, strategic trade-offs, risks, and potential value Proven ability to integrate scientific, clinical, market, patient, payer, competitive, operational, and financial information into clear strategic recommendations Demonstrated success identifying and prioritizing lifecycle opportunities such as new indications, populations, formulations, evidence programs, access strategies, delivery approaches, or strategic partnerships Strong executive presence with the ability to communicate complex issues, scenarios, risks, and recommendations clearly and succinctly to senior leadership and governance bodies Demonstrated ability to establish clear accountability, address performance or alignment issues directly, and create a productive environment for constructive debate and decision-making Knowledge of relevant legal, regulatory, and compliance requirements governing pharmaceutical development, Medical Affairs activities, product promotion, scientific exchange, and interactions with external stakeholders Ability to operate successfully in a complex, evolving organization while managing multiple priorities and maintaining an enterprise perspective Direct experience developing or leading strategy for at least one launched pharmaceutical or biotechnology brand is required

Equal Opportunity and Inclusion

Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

Salary and Benefits

The annual base salary we reasonably expect to pay is $227,000.00-$398,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. We are a top place to work. Neurocrine Biosciences was named one of the FORTUNE Best Workplaces in Biopharma™ 2025. We were also named a Great Place to Work® Certified company. ©2025 Fortune Media IP Limited. All rights reserved. Used under license.

Our Values

• PASSION: We are driven and love what we do. We are committed to our goals and to making a difference.
• INTEGRITY: We do the right thing for patients and our community. We take accountability. We speak up.
• COLLABORATION: We trust one another. We are inclusive. We are respectful. We are transparent. Together we succeed.
• INNOVATION: We seek and create optimal solutions.
• TENACITY: We do not quit. We adapt. We accomplish what others cannot.

Join Us

Come join our team during this exciting time of growth and opportunities!