Executive Leader, Translational Medicine & Strategy

BioSpace; Cambridge (MA); On-site; USD 272,000 - 490,000; Full time

Benefits offered by this job

Healthcare coverage

Well-being programs

Generous PTO

Job summary

Moderna seeks a visionary Head of Translational Medicine to unify translational medicine, translational research, and clinical pharmacology into a high-impact organization. You will shape strategy across discovery to lifecycle management, aligning biological insights with biomarkers and quantitative pharmacology to accelerate decision-making.

This senior leader will oversee a large, multidisciplinary team, partner with regulators and scientific leaders, and drive innovation across oncology and

Qualifications

• Advanced degree (PhD, MD, PharmD, or equivalent) in a relevant scientific field.
• 15+ years of experience across translational science, clinical pharmacology, and/or drug development, with at least 10 years in a leadership role.
• Deep expertise spanning translational medicine, biomarker strategy, experimental medicine, and quantitative pharmacology.
• Demonstrated ability to develop scientific hypotheses on human disease and translate this between the clinic and the laboratory.
• Demonstrated success influencing development strategy, including dose selection, study design, and regulatory interactions.
• Strong understanding of the end-to-end drug development process, from discovery through commercialization.
• Strong publication record and ability to represent Moderna externally to scientific community.
• Proven ability to lead large, multidisciplinary teams and operate effectively in a complex matrix environment.
• Experience mentor, hiring, and growing talented scientists.
• Track record of driving innovation and delivering measurable impact across a portfolio.
• Exceptional communication and influencing skills, with the ability to translate complex science into strategic decisions.

Responsibilities

• Define and lead an integrated, end-to-end translational strategy across Translational Medicine, Translational Research, and Clinical Pharmacology/Pharmacometrics.
• Establish a unified framework connecting biological insights, biomarkers, and quantitative pharmacology to enable rapid, data-driven decision-making.
• Ensure alignment of translational strategies with overall program and portfolio objectives, including development pathways, target product profiles, and regulatory strategies.
• Lead translational input into governance, ensuring rigorous, data-driven go/no-go decisions across the pipeline.
• Lead and unify a high-performing, multidisciplinary translational organization, connecting scientific, clinical, and quantitative capabilities into a cohesive model.
• Serve as a senior leader and thought partner across Research and Development, influencing strategy, prioritization, and execution.
• Represent Moderna’s translational strategy externally, engaging regulators, scientific leaders, and partners to shape scientific direction.

Skills

Leadership experience

Translational medicine

Biomarker strategy

Regulatory interactions

Pharmacology

Data-driven decisions

Education

Advanced degree in relevant field

Tools

Molecular assays

Sequencing

CDx

Immune monitoring

Job description

Moderna seeks a visionary Head of Translational Medicine to unify translational medicine, translational research, and clinical pharmacology into a high-impact organization. You will shape strategy across discovery to lifecycle management, aligning biological insights with biomarkers and quantitative pharmacology to accelerate decision-making.

This senior leader will oversee a large, multidisciplinary team, partner with regulators and scientific leaders, and drive innovation across oncology and