Executive Director, Myeloma Clinical Development Lead

Legend Biotech USA, Inc.; New Jersey; On-site; USD 294,000 - 387,000; Full time

Job summary

Legend Biotech in Somerset, NJ, seeks an Executive Director, Multiple Myeloma Pipeline Lead to provide strategic, scientific, and medical leadership across the development lifecycle, from first‑in‑human to registration‑enabling programs.

You will lead cross‑functional teams, drive integrated development plans, oversee IND submissions and regulatory interactions, and help differentiate the portfolio through biomarker and risk‑based strategies.

Qualifications

• MD/MD-PhD or equivalent medical degree required; board certification in hematology or oncology is required.
• Minimum of 6 years of clinical development experience in the biopharmaceutical industry and/or academic medicine, with substantial experience in hematologic malignancies and multiple myeloma.
• Substantial expertise in multiple myeloma clinical development is strongly preferred, including experience across relapsed/refractory and earlier-line treatment settings.
• Experience designing and leading early clinical development programs, including first-in-human studies, dose escalation, dose expansion, and proof-of-concept generation.
• Experience leading cross-functional development teams in a matrixed, global environment is preferred.

Responsibilities

• Serve as the clinical lead for the Multiple Myeloma Pipeline, providing strategic, scientific, and medical leadership across the development lifecycle.
• Develop and maintain an integrated clinical development strategy across the Multiple Myeloma Pipeline, ensuring alignment with corporate objectives and regulatory expectations.
• Lead or contribute to pivotal study strategy, protocol design, data interpretation, and registration-enabling planning.
• Provide clinical leadership for regulatory submissions, health authority briefing packages, and publications.
• Mentor and lead the pipeline clinical development team to deliver high-quality clinical evidence.

Skills

Clinical leadership

Strategic development planning

Cross-functional collaboration

Regulatory interactions

IND submissions experience

Communication skills

Education

MD/MD-PhD or equivalent

Board certification in hematology or oncology

Job description

Legend Biotech in Somerset, NJ, seeks an Executive Director, Multiple Myeloma Pipeline Lead to provide strategic, scientific, and medical leadership across the development lifecycle, from first‑in‑human to registration‑enabling programs.

You will lead cross‑functional teams, drive integrated development plans, oversee IND submissions and regulatory interactions, and help differentiate the portfolio through biomarker and risk‑based strategies.