Executive Director, Biostatistics

Vertex Pharmaceuticals Inc (US); United States; Hybrid; USD 272,000 - 407,000; Full time

Benefits offered by this job

Health and well-being programs

Job summary

Vertex Pharmaceuticals Inc (US) is seeking an Executive Director of Biostatistics to lead statistical functions across multiple therapeutic areas. The role includes scientific contributions, driving operational excellence, and a highly visible, collaborative partnership with R&D and Global Medical Affairs.

The incumbent will champion innovative trial designs and set strategic direction for data operations and reporting.

Qualifications

• MS or PhD in Statistics or Biostatistics is required.
• Minimum 15 years of relevant experience or equivalent combination of education and experience.
• Proven ability to lead high-performing teams and influence at the executive level.
• Expert in statistical methodologies and industry trends with agile learning.

Responsibilities

• Lead scientific statistical methodology to impact Vertex portfolios with best-practice and novel approaches.
• Own biometrics processes, SOPs, process maps, training, and software/tools as appropriate.
• Provide statistical support for early to late clinical studies, post-marketing studies, and RWE analyses.
• Drive innovative trial designs to improve efficiency and inform executive decisions.
• Serve on Biostatistics Leadership Team to set vision and execution for data operations, statistics, and reporting.
• Represent Vertex externally in industry, academic, and regulatory forums.

Skills

Statistical methods

Leadership

Biostatistics leadership

Executive communication

Education

MS or PhD in Statistics/Biostatistics

Job description

Job Description General Summary: The Executive Director of Biostatistics is a strategic, dynamic, and empowered leader, overseeing statistical functions in support of multiple company therapeutic areas or portfolios. In addition, The incumbent is responsible for the methodological and quantitative scientific contributions of their group while simultaneously driving operational excellence. The Executive Director will have a highly visible and collaborative role, partnering across various R&D functions to generate evidence in support of Vertex pipelines/products.

Key Duties and Responsibilities:

• Is responsible for leading/driving scientific statistical methodological expertise to impact the Vertex portfolio by application of both best in class and novel statistical approaches as part of unified Development strategies. This includes oversight of quantitative methods deployed across the portfolio with an eye towards efficiency and innovation.
• Serve as subject matter expert and owner when appropriate for key biometrics processes and associated operating model(s) related to Biostatistics SOPs, process maps, training and software/tools
• Own statistical support in the therapeutic areas and/or Global Medical Affairs he/she leads including early/late clinical developments, post-marketing studies, RWE studies and/or analyses supporting reimbursement
• Drive innovative trial designs in complex/fast changing environment to improve trial efficiency and shape the views of the executive team on important matters
• Serve as a key Leader on the Biostatistics Leadership Team to help set and drive vision and execution with respect to data operations, statistics, and statistical reporting/analytics.
• Represent Vertex externally, demonstrating scientific leadership and collaborating in industry, academic and regulatory forums as appropriate.

Knowledge and Skills:

• Outstanding communication including clarity in writing including excellence in scientific/technical/process writing, influential speech and negotiation, ability to explain complex concepts to others, willingness and ability to engage in scientific discourse at the executive level.
• Demonstrated experience developing and leading high performing teams.
• Expert in statistical methodology including best practices and new industry trends. Agile learner and change agent.
• Executive presence and high degree of emotional intelligence

Education and Experience:

• An M.S or Ph.D. in Statistics or Biostatistics
• 15 years of relevant work experience or the equivalent combination of education and experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range: $271,600 - $407,400 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1.

Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X

We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.