Enterprise Initiatives Manager

1010 Genentech USA, Inc.; South San Francisco (CA); Remote; USD 147,000 - 273,000; Full time

Benefits offered by this job

Discretionary annual bonus

Job summary

Genentech, a Roche company, seeks an Enterprise Initiatives Manager to translate CE priorities into executable initiatives with clear ownership and milestones. You will lead cross-functional teams, manage risks, and ensure outcomes align with the CE portfolio.

In this role, you will partner with senior field sponsors, coordinate across Regions and enterprise functions, and maintain governance and performance dashboards. Travel may be required based on business needs.

Qualifications

• Bachelor's degree required.
• 8-10 years of pharmaceutical, biotechnology, consulting, commercial, program management, transformation, and/or operations experience including leading, coaching or mentoring others strongly preferred.
• Demonstrated experience leading complex cross-functional initiatives from definition through implementation.
• Experience partnering with senior sponsors and translating strategy into executable plans.
• Strong project/program management, facilitation, and stakeholder leadership capabilities.
• Demonstrated ability to influence across a complex matrixed organization.
• Strong communication, executive presentation, analytical, and problem-solving skills.
• Ability and willingness to travel as required for internal and external business meetings.

Responsibilities

• Lead planning and delivery of selected CE enterprise initiatives from definition through implementation and outcome review.
• Translate approved priorities into clear workplans with owners, milestones, dependencies, measures, and decision points.
• Maintain disciplined execution against agreed scope, timing, and outcomes.
• Coordinate implementation across Regions, teams, and enterprise functions when work spans organizational boundaries.
• Ensure initiatives transition effectively from planning into sustained business ownership when appropriate.
• Serve as the operational partner to HEDs, Regional leaders, and other field partners who sponsor enterprise work.
• Help sponsors clarify the business problem, desired outcome, scope, stakeholders, and decisions required.
• Carry the operational coordination burden so sponsors can focus on strategic direction and business leadership.
• Create transparent sponsor updates that highlight progress, risks, decisions, and support needed.
• Ensure field-sponsored work remains connected to broader CE priorities and does not become isolated or duplicative.
• Mobilize the right partners across CE, Regions, RBO, DDA, L&SD, CPO, Field Medical, GPAA, and other functions as needed.
• Clarify roles, handoffs, dependencies, and shared commitments across initiative teams.
• Facilitate working sessions and decisions that move complex enterprise work forward.
• Identify and resolve execution barriers at the appropriate level, escalating when needed.
• Promote common execution standards while adapting the operating approach to the needs of each initiative.
• Define practical measures of progress, adoption, impact, and intended business outcomes for enterprise initiatives.
• Maintain clear visibility to risks, dependencies, decisions, and unresolved issues.
• Escalate material risks and tradeoffs early with clear recommendations for action.
• Lead outcome reviews and capture lessons that can improve future enterprise work.
• Ensure decisions and follow-up actions are documented, owned, and completed.
• Lead, coach, and develop Enterprise Operations Leads assigned to enterprise initiatives.
• Set clear expectations for planning, stakeholder management, communication, risk management, and execution quality.
• Allocate team capacity across initiatives based on business priority, complexity, and timing.
• Build reusable initiative management tools, templates, and ways of working.
• Contribute to common Enterprise Operations standards, talent practices, and continuous improvement.

Skills

Cross-functional leadership

Project management

Stakeholder leadership

Strategic planning

Communication

Influence without authority

Facilitation

Risk management

Travel flexibility

Education

Bachelor's degree

Graduate-level degree (MBA or advanced life sciences)

Job description

From the beginning, Genentech has been a team of highly dedicated, passionate individuals. We are a place where people are united around a single purpose and an ambitious vision. Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key. Utilizing innovative methods to identify patients who may benefit from treatment, we must take a highly strategic approach to patient access while assisting patients and their caregivers to navigate the healthcare system.

POSITION SUMMARY

The Enterprise Initiatives Manager is responsible for translating selected CE enterprise priorities and field-sponsored opportunities into well-governed, executable initiatives with clear ownership, milestones, measures, and accountability. This role provides the operational leadership that allows HEDs, Regional leaders, and other field partners to sponsor enterprise work without carrying the day-to-day coordination burden alone. The manager leads cross-functional execution, manages risks and dependencies, and ensures enterprise initiatives deliver intended outcomes while remaining connected to the broader CE portfolio and governance system.

SCOPE & KEY RESPONSIBILITIES

Enterprise Initiative Delivery

Lead planning and delivery of selected CE enterprise initiatives from definition through implementation and outcome review. Translate approved priorities into clear workplans with owners, milestones, dependencies, measures, and decision points. Maintain disciplined execution against agreed scope, timing, and outcomes. Coordinate implementation across Regions, teams, and enterprise functions when work spans organizational boundaries. Ensure initiatives transition effectively from planning into sustained business ownership when appropriate.

Field Sponsor Partnership

Serve as the operational partner to HEDs, Regional leaders, and other field partners who sponsor enterprise work. Help sponsors clarify the business problem, desired outcome, scope, stakeholders, and decisions required. Carry the operational coordination burden so sponsors can focus on strategic direction and business leadership. Create transparent sponsor updates that highlight progress, risks, decisions, and support needed. Ensure field-sponsored work remains connected to broader CE priorities and does not become isolated or duplicative.

Cross-Functional Orchestration

Mobilize the right partners across CE, Regions, RBO, DDA, L&SD, CPO, Field Medical, GPAA, and other functions as needed. Clarify roles, handoffs, dependencies, and shared commitments across initiative teams. Facilitate working sessions and decisions that move complex enterprise work forward. Identify and resolve execution barriers at the appropriate level, escalating when needed. Promote common execution standards while adapting the operating approach to the needs of each initiative.

Outcome Measurement, Risk & Escalation

Define practical measures of progress, adoption, impact, and intended business outcomes for enterprise initiatives. Maintain clear visibility to risks, dependencies, decisions, and unresolved issues. Escalate material risks and tradeoffs early with clear recommendations for action. Lead outcome reviews and capture lessons that can improve future enterprise work. Ensure decisions and follow-up actions are documented, owned, and completed.

Team Leadership & Execution Standards

Lead, coach, and develop Enterprise Operations Leads assigned to enterprise initiatives. Set clear expectations for planning, stakeholder management, communication, risk management, and execution quality. Allocate team capacity across initiatives based on business priority, complexity, and timing. Build reusable initiative management tools, templates, and ways of working. Contribute to common Enterprise Operations standards, talent practices, and continuous improvement.

KEY DELIVERABLES

• Enterprise initiative charters and workplans
• Field-partner sponsor plans and stakeholder maps
• Milestone, dependency, and decision tracking
• Initiative status and escalation materials
• Cross-functional execution plans
• Executive dashboards and decision materials
• Outcome reviews and lessons learned
• Enterprise initiative standards, templates, and playbooks

MINDSET & CAPABILITIES

• Strong enterprise operator who can move from ambiguity to action
• Trusted partner to senior field and enterprise sponsors
• Able to translate strategic intent into executable work
• Highly effective at influencing without formal authority
• Strong facilitator who creates clarity across diverse stakeholders
• Proactive in identifying risks, dependencies, and decision needs
• Disciplined about outcomes, ownership, and follow-through
• Strong communication and executive synthesis capabilities
• Comfortable managing multiple complex initiatives simultaneously
• Collaborative people leader and developer of talent
• Growth mindset with a focus on learning and continuous improvement

REQUIRED QUALIFICATIONS

• Bachelor's degree required
• 8-10 years of pharmaceutical, biotechnology, consulting, commercial, program management, transformation, and/or operations experience including leading, coaching or mentoring others strongly preferred
• Demonstrated experience leading complex cross-functional initiatives from definition through implementation
• Experience partnering with senior sponsors and translating strategy into executable plans
• Strong project/program management, facilitation, and stakeholder leadership capabilities
• Demonstrated ability to influence across a complex matrixed organization
• Strong communication, executive presentation, analytical, and problem-solving skills
• Ability and willingness to travel as required for internal and external business meetings

PREFERRED QUALIFICATIONS

• Graduate-level degree (e.g., MBA or advanced life sciences degree)
• Prior field operations, enterprise transformation, or commercial operations experience
• Experience supporting field-sponsored or cross-regional initiatives

Location

Location: This position can be based in SSF or Remote. Relocation benefits are not available.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

The expected salary range for this position based on the primary location of SSF CA is $147,000.00 - $273,000 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.