Enterprise Architect Director

Neurocrine Biosciences; San Diego (CA); On-site; USD 196,000 - 267,000; Full time

Benefits offered by this job

Annual bonus

Equity-based long term incentive

Health benefits

Retirement plan

Job summary

Neurocrine Biosciences is seeking a Director, IT – Enterprise Architect to lead the enterprise architecture program and translate business capabilities into scalable architectures. You will partner with research, development, manufacturing and QA to align IT strategy with company goals and ensure compliant, cost-effective solutions.

The role requires deep expertise in integration, cloud, data architecture and governance, with a track record of guiding complex cross-functional programs and

Qualifications

• Bachelor's degree in computer science, information technology, engineering, or related field.
• 8+ years in enterprise or solution architecture; 5+ years leading architecture initiatives.
• Master's degree preferred; MBA optional.

Responsibilities

• Define and drive enterprise architecture vision and multi-year roadmap.
• Establish governance, design principles, and architecture standards.
• Lead architecture governance forums and exception management.
• Conduct capability mapping and identify gaps and priorities.
• Provide guidance for end-to-end solutions across ERP/CRM/PLM/SCM/quality systems.
• Define integration, API strategy, and middleware standards.
• Define data/analytics architecture directions and data governance.
• Shape cloud, security, and AI architecture patterns.
• Support M&A, divestiture, and system separations.

Skills

Enterprise architecture

API management

Cloud architecture

AI/Generative AI

Automation

Low-code solutions

Agile delivery

Cross-functional leadership

Communication

Problem solving

Strategic thinking

Education

Bachelor's degree in Computer Science/IT/Engineering or related field

Master's degree in related field (MBA preferred)

Tools

Databricks

Snowflake

Redshift

AWS

Azure

CI/CD tooling

Job description

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)

About the Role:

The Director, IT – Enterprise Architect serves as the enterprise architecture thought leader and provides strategic leadership for the enterprise architecture practice, defining the target-state architecture, standards, and multi-year technology roadmap that align IT investment with enterprise strategy. This role partners with business and IT leaders across research, drug development, manufacturing, quality, commercial, and G&A to translate business capability needs into scalable, compliant, and cost-effective solution architectures. The Director establishes the architecture governance model that guides enterprise technology and architecture decisions in validated and non-validated environments.

Your Contributions (include, but are not limited to):

Define and drive the enterprise architecture vision, current and target-state architecture, and multi-year technology roadmap aligned to enterprise business strategy, Translating strategic business priorities into actionable technology direction and investment priorities Establish, evolve and drive adoption of enterprise architecture frameworks, reference architectures, design principles, and architecture standards that enable consistent enterprise technology decisions Lead the architecture governance process, including design authority forums, architecture review boards, and exception management Conduct business capability assessments and capability-to-application mapping to identify gaps, redundancies, and investment priorities Provide strategic architecture direction and expert guidance for end-to-end solutions across core enterprise platforms, including ERP, CRM, PLM, SCM, quality, laboratory, and financial systems Define and influence enterprise-wide integration and API strategy, including middleware standards and B2B integration approaches Define the enterprise data and analytics architecture direction and standards, covering data platforms, data domains, governance, and consumption patterns, in partnership with relevant functional experts Establish and influence enterprise cloud, security, and AI architecture patterns in partnership with Infrastructure, Information Security, and Data Engineering functions Ensure architecture designs satisfy GxP, data integrity, privacy, and computer system validation requirements, including 21 CFR Part 11 and GAMP 5 expectations, on a case-by-case basis Provide strategic architecture leadership on M&A, divestiture, and in-licensing activity, including system integration, separation, and transition planning Partner with sourcing and vendor management on technology selection, vendor evaluation, and build-versus-buy recommendations Manage the architecture practice roadmap, budget, and external partner resources to deliver committed outcomes on time and within approved budget Communicating and influencing alignment on architecture direction to executive stakeholders, translating complex technical concepts into business impact, enterprise risk and investment rationale Anticipate and evaluate emerging technologies and industry trends and recommend and influence adoption of technologies and patterns that advance enterprise capability and efficiency

Requirements:

Bachelor's degree in computer science, Information Technology, Engineering, or related field AND 12+ years of progressive IT experience, including 8+ years in enterprise or solution architecture and 5+ years providing technical leadership for enterprise architecture initiatives, cross-functional teams, or complex technology programs Master's degree in computer science, Information Technology, Engineering, or a related field (MBA preferred) and 10+ years as noted above Strong command of integration architecture, including API management, event-driven patterns, and enterprise middleware Working knowledge of modern data architecture, including cloud data platforms (Databricks, Snowflake, Redshift), lakehouse patterns, and data governance models Experience architecting on public cloud (AWS or/and Azure), including landing zones, cost optimization, and cloud security patterns Demonstrated knowledge and experience evaluating and architecting AI, generative AI, automation, and low-code solutions, including use case qualification and platform selection Proven experience leading architecture for enterprise-scale portfolio rationalization and modernization programs, including architecture workstreams for mergers, acquisitions, divestitures, and system separations Familiarity with software development practices, including agile/lean delivery, version control, code review, and CI/CD Recognized internally as a thought leader and expert in expertise architecture, with broad expertise across related technology disciplines Influences and negotiates with senior and executive leadership to secure alignment on technology direction and investment Excellent communication, problem-solving, and analytical thinking skills Sees the broader picture and anticipates upstream and downstream impacts across multiple functions, departments, and external partners Demonstrated ability to lead complex, cross-functional programs and initiatives involving significant scope, interdependencies, risk, and organizational impact Sets direction in ambiguous and complex situations, exercising advanced judgement, and making well-informed decisions with incomplete information

#LI-CL1 Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

The annual base salary we reasonably expect to pay is $195,700.00-$267,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

We are a top place to work. Neurocrine Biosciences was named one of the FORTUNE Best Workplaces in Biopharma™ 2025. We were also named a Great Place to Work® Certified company. ©2025 Fortune Media IP Limited. All rights reserved. Used under license.

OUR VALUES:

• PASSION: We are driven and love what we do. We are committed to our goals and to making a difference.
• INTEGRITY: We do the right thing for patients and our community. We take accountability. We speak up.
• COLLABORATION: We trust one another. We are inclusive. We are respectful. We are transparent. Together we succeed.
• INNOVATION: We seek and create optimal solutions.
• TENACITY: We do not quit. We adapt. We accomplish what others cannot.

Come join our team during this exciting time of growth and opportunities!