Electrophysiology Research Scientist: Patch-Clamp Expert

Mindspan Institute; Cambridge (MA); On-site; USD 120,000 - 159,000; Full time

Benefits offered by this job

Health benefits

Matching retirement

Job summary

Mindspan Institute in Cambridge, MA seeks an exceptional electrophysiology research scientist to operate patch-clamp platforms and lead high‑throughput experiments. This is an intensely hands‑on, in‑person role: you will perform manual and automated whole‑cell recordings in mammalian brain slices, troubleshoot experiments, and interpret data.

Collaborating with engineers and scientists, you will optimize rigs, develop standardized protocols, and push the limits of what can be measured while

Qualifications

• PhD in neuroscience or related field, or equivalent experience.
• Hands-on experience with whole-cell patch-clamp electrophysiology in mammalian brain slices.
• Strong understanding of electrophysiological recording techniques and neuronal physiology.
• Excellent manual patch-clamp skills and steady hands.

Responsibilities

• Generate high-quality monosynaptically paired whole-cell patch-clamp recordings manually and with automation.
• Troubleshoot experiments, analyze data, and interpret results to reveal circuit physiology.
• Collaborate with engineers to improve workflows and standardize high-throughput protocols.

Skills

Patch-clamp

Electrophysiology

Automation experience

Python MATLAB

Education

PhD in neuroscience or related field

Tools

Python

MATLAB

Job description

Mindspan Institute in Cambridge, MA seeks an exceptional electrophysiology research scientist to operate patch-clamp platforms and lead high‑throughput experiments. This is an intensely hands‑on, in‑person role: you will perform manual and automated whole‑cell recordings in mammalian brain slices, troubleshoot experiments, and interpret data.

Collaborating with engineers and scientists, you will optimize rigs, develop standardized protocols, and push the limits of what can be measured while