Research Associate: Tissue Processing & Patch-Clamp

Allen Institute; Seattle (WA); On-site; USD 54,000 - 66,000; Full time

Job summary

The Allen Institute in Seattle invites applications for a Research Associate I – Tissue Processing & Electrophysiology. The role focuses on generating high-quality patch-clamp electrophysiology and transcriptomic data to classify brain cell types and support brain science projects.

The candidate will perform surgical procedures, tissue dissections, and work with mouse, human, NHP, and other tissues in a high-throughput setting, following SOPs and regulatory guidelines.

Qualifications

• Bachelor's degree in a life science or related field.
• 1+ years of related work experience and/or training preferred.
• Experience with patch-seq, high-throughput tissue processing, and electrophysiology data desirable.
• Strong manual dexterity and attention to detail.

Responsibilities

• Perform acute surgical procedures and tissue dissections.
• Handle mice and other laboratory animals.
• Process mouse, human, non-human primate (NHP) and porpoise brain tissue.
• Perform patch-seq experiments from mouse, NHP and human brain slice preparations.
• Apply established QC criteria and help develop new analytical criteria across electrophysiology, molecular biology, and imaging data.
• Pilot and optimize tissue preparations for advanced imaging techniques.
• Work in dynamic core facilities with tight deadlines.
• Dissociate and prepare single-cell/nuclei samples for analysis.
• Cell and tissue histological staining.
• Follow SOPs, GMP-like practices, and regulatory requirements.
• Maintain accurate laboratory documentation and reporting.

Skills

Manual dexterity

Attention to detail

Independent work

Team collaboration

Education

Bachelor's degree in life science or related field

Tools

Microsoft Office

Job description

The Allen Institute in Seattle invites applications for a Research Associate I – Tissue Processing & Electrophysiology. The role focuses on generating high-quality patch-clamp electrophysiology and transcriptomic data to classify brain cell types and support brain science projects.

The candidate will perform surgical procedures, tissue dissections, and work with mouse, human, NHP, and other tissues in a high-throughput setting, following SOPs and regulatory guidelines.