Early-Phase Oncology PI & Clinical Leader

START Research; Charlotte (NC); Hybrid; USD 180,000 - 240,000; Full time

Benefits offered by this job

401(k) retirement savings plan withem­

Annual performance bonus

Paid time off and holidays

Medical/dental/vision coverage

Life and disability insurance

Employee Assistance Program (EAP)

Flexible FSA and HSA

Job summary

START Center for Cancer Research in Charlotte, NC, seeks a Clinical Principal Investigator to lead early-phase oncology trials, oversee protocol development, and ensure regulatory compliance. You will manage medical direction, sponsor relationships, and data integrity at the site.

The role requires an MD, board certification in Hematology/Oncology, and strong clinical trials experience with a passion for collaborative care and patient safety.

Qualifications

• MD or equivalent.
• Board Certified in Hematology and/or Medical Oncology.
• Clinical trials experience with a strong interest in drug development.
• Ability to critically analyze clinical scientific data and literature.
• Understanding of GCP principles, safety and adverse event reporting, FDA regulations, and biomedical research ethics.
• A passion for providing excellent clinical care and for working in a collaborative / team-oriented environment.

Responsibilities

• Manage early phase clinical trials with medical direction and protocol reviews per investigational plan and GCP.
• Provide medical and scientific feasibility for sponsor inquiries to drive growth.
• Lead a matrix team overseeing early phase oncology trial conduct.
• Ensure participant safety, data credibility, and confidentiality at the site.
• Develop relationships with Sponsors/ CROs and provide guidance to operational staff.
• Lead quality improvement efforts and foster research excellence.
• Develop strategies to enhance patient recruitment and retention in trials.

Skills

Leadership

Communication

Analytical skills

Teamwork

Education

MD

Board Certified in Hematology/Oncology

Job description

START Center for Cancer Research in Charlotte, NC, seeks a Clinical Principal Investigator to lead early-phase oncology trials, oversee protocol development, and ensure regulatory compliance. You will manage medical direction, sponsor relationships, and data integrity at the site.

The role requires an MD, board certification in Hematology/Oncology, and strong clinical trials experience with a passion for collaborative care and patient safety.