Downstream Process Scientist - High-Throughput Chromatography

Rangam; Andover (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Rangam in Andover, MA seeks a highly skilled scientist to advance chromatography science through high-throughput experimentation and laboratory automation. You will lead TECAN-based automated purification workflows, design experiments, and translate findings into scalable downstream processes.

Emphasis on DOE, data analysis, and mechanistic understanding, with collaboration across automation, engineering, digital and analytical teams to accelerate process development timelines.

Qualifications

• Hands-on experience programming TECAN liquid-handling platforms.
• Proven automated protein purification workflows.
• Experience in downstream process development for biologics.
• Strong chromatography fundamentals and protein purification.
• Ability to design and interpret laboratory studies.
• Excellent data analysis and scientific communication skills.

Responsibilities

• Program and operate TECAN platforms to develop automated purification workflows.
• Perform high-throughput studies to explore process design space.
• Translate lab findings into scalable downstream processes.
• Collaborate with automation, engineering, digital and analytical teams.
• Apply DOE and statistical methods to drive experiments.

Skills

TECAN programming

Automated protein purification

High-throughput experimentation

DOE

Statistical modeling

Downstream processing

Chromatography

Data analysis

Education

PhD in Chemical Engineering or related

Tools

TECAN hardware suite

Laboratory automation software

Job description

Rangam in Andover, MA seeks a highly skilled scientist to advance chromatography science through high-throughput experimentation and laboratory automation. You will lead TECAN-based automated purification workflows, design experiments, and translate findings into scalable downstream processes.

Emphasis on DOE, data analysis, and mechanistic understanding, with collaboration across automation, engineering, digital and analytical teams to accelerate process development timelines.