Downstream Process Engineer for Startup & Scale-Up

Piper Companies; Cary (NC); On-site; USD 175,000 - 190,000; Full time

Benefits offered by this job

PTO

Paid holidays

Medical insurance

Dental insurance

Vision insurance

Job summary

Piper Companies is seeking a Downstream Equipment Engineer to lead the startup and commissioning of a new commercial-scale biopharmaceutical facility. You will provide technical leadership for downstream purification startup efforts, equipment readiness, process validation, technology transfer, and operational excellence.

You will collaborate with Manufacturing, MSAT, Validation, Quality, and Engineering to ensure successful process transfer and commercial readiness, and you will provide

Qualifications

• Bachelor's degree in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
• 7+ years of downstream bioprocessing experience in a GMP manufacturing environment.
• Experience with commercial-scale chromatography, filtration, and purification processes.
• Experience supporting facility startup, commissioning, qualification, or process validation activities is highly desirable.
• Strong troubleshooting, communication, and cross-functional collaboration skills.

Responsibilities

• Support qualification, and startup of downstream processing equipment and systems.
• Lead troubleshooting and optimization of chromatography skids and columns.
• Partner with Manufacturing, MSAT, Validation, Quality, and Engineering teams to ensure successful process transfer and commercial readiness.
• Provide on-floor technical support/troubleshooting support during engineering, validation, and commercial manufacturing campaigns.
• Author and review SOPs, batch records, protocols, and technical reports.

Skills

Chromatography

Filtration

Process optimization

Troubleshooting

Cross-functional collaboration

Technical leadership

Education

Bachelor's degree in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field

Tools

Chromatography systems

Process validation protocols

Job description

Piper Companies is seeking a Downstream Equipment Engineer to lead the startup and commissioning of a new commercial-scale biopharmaceutical facility. You will provide technical leadership for downstream purification startup efforts, equipment readiness, process validation, technology transfer, and operational excellence.

You will collaborate with Manufacturing, MSAT, Validation, Quality, and Engineering to ensure successful process transfer and commercial readiness, and you will provide