DMPK LC-MS Bioanalysis Scientist - PK & Modality Innovation

Zealand Pharma; Cambridge (MA); On-site; USD 110,000 - 170,000; Full time

Job summary

Zealand Pharma is expanding its R&D presence in Cambridge, MA to advance DMPK capabilities for diverse drug modalities. Join a cross-functional team to develop LC-MS methods, design PK studies, and interpret data that informs project decisions.

You will contribute to building a new research center, working on complex molecules like antibodies and conjugates, and collaborating across Discovery, Translational, Toxicology, and Clinical Pharmacology teams.

Qualifications

• PhD in pharmaceutical sciences or related field with 0–3 years industry/postdoc; MS with ~3–6 years industry experience; or BS/BA with ~5–8+ years industry experience.
• Hands-on LC-MS bioanalysis and assay development experience.
• Experience in PK study design, data interpretation, and translating DMPK insights into actionable recommendations.
• Experience with bioanalysis of complex molecules (peptides, antibodies, conjugates) and familiarity with ADME assays.

Responsibilities

• Develop and advance DMPK discovery platforms and LC-MS bioanalysis for complex drug modalities.
• Execute LC-MS bioanalysis workflow from input to PK study design, method development, sample analysis and data reporting.
• Support PK and metabolite identification across discovery projects.
• Design and conduct in vitro assays such as metabolic stability experiments and other DMPK assays.
• Drive continuous improvement of DMPK workflows through digital and automation-enabled approaches.

Skills

LC-MS bioanalysis

Assay development

PK workflow interpretation

Education

PhD in pharmaceutical sciences

MS in related field

BS/B.A. in related field

Tools

LC-MS instrumentation

Job description

Zealand Pharma is expanding its R&D presence in Cambridge, MA to advance DMPK capabilities for diverse drug modalities. Join a cross-functional team to develop LC-MS methods, design PK studies, and interpret data that informs project decisions.

You will contribute to building a new research center, working on complex molecules like antibodies and conjugates, and collaborating across Discovery, Translational, Toxicology, and Clinical Pharmacology teams.