Director, Translational Sciences & Biomarker Strategy

Scorpion Therapeutics; Watertown (MA); On-site; USD 195,000 - 218,000; Full time

Benefits offered by this job

Salary range

Annual performance bonus

Medical, dental, vision insurance

401K match

PTO 20+ days

Sponsorship not required

Job summary

Scorpion Therapeutics is seeking a senior Translational Sciences leader to define and drive the translational strategy across our early clinical pipeline, ensuring alignment with corporate objectives and clinical priorities.

You will own translational strategy for T1D and CAR-T programs, integrating biomarker objectives into clinical protocols, sample collection plans, and trial timelines. Lead assay development and CRO partnerships to ensure readiness and regulatory alignment.

Qualifications

• PhD or advanced degree in Immunology, Translational Medicine, Cell & Gene Therapy, or related field.
• 10+ years in clinical translational science/biomarker development with early clinical leadership.
• Experience in T1D, autoimmune disease, CAR-T, or cell/gene therapy is highly preferred.

Responsibilities

• Define and drive translational science strategy across the early clinical pipeline.
• Lead translational strategy for T1D and CAR-T programs; align with clinical protocols and timelines.
• Represent translational sciences at conferences, regulatory agencies, and partner meetings.
• Oversee development and execution of translational and biomarker strategies for early-phase trials.
• Define and lead clinical biomarker objectives, contexts of use, and analysis plans.
• Interpret patient-derived translational datasets to inform program strategy.
• Partner with Early Development, Clinical Operations, Regulatory, and Medical teams.
• Build and lead the Translational Sciences team; manage resources, headcount, and budget.

Skills

Clinical biomarker development

Immune monitoring

Translational data interpretation

Education

PhD or advanced degree in Immunology/Translational Medicine/Cell & Gene Therapy

Job description

Scorpion Therapeutics is seeking a senior Translational Sciences leader to define and drive the translational strategy across our early clinical pipeline, ensuring alignment with corporate objectives and clinical priorities.

You will own translational strategy for T1D and CAR-T programs, integrating biomarker objectives into clinical protocols, sample collection plans, and trial timelines. Lead assay development and CRO partnerships to ensure readiness and regulatory alignment.