Director, Translational Cardiovascular Medicine (Hybrid)

MSD; Boston (MA); Hybrid; USD 260,000 - 410,000; Full time

Job summary

Merck & Co., Inc. in the United States (Boston, MA) seeks a Principal Scientist/Director in Translational Medicine for Cardiovascular disease.

You will lead early clinical development, design biomarker strategies, and guide biomarker platforms from PoC through Phase 4, interfacing across discovery, regulatory, and late-stage clinical teams. You will validate targets with clinical insights, drive early clinical plans for Lead Optimization, and ensure timely execution of Phase I studies with

Qualifications

• Proven track record in clinical medicine or clinical research.
• Publications or presentations demonstrating scientific scholarship.
• Ability to collaborate across therapeutic areas.

Responsibilities

• Lead early clinical development strategy for novel therapy programs (Phases 1–4).
• Develop and validate biomarker platforms and clinical pharmacology plans.
• Identify targets by partnering with discovery teams and validate clinically.
• Provide clinical pharmacology support for worldwide regulatory filing.
• Communicate study results to governance bodies and stakeholders.

Skills

Cardiology

Cardiovascular Medicine

Clinical Trials

Nephrology

Scientific Research

Translational Medicine

Translational Research

Education

MD or MD/PhD

Job description

Merck & Co., Inc. in the United States (Boston, MA) seeks a Principal Scientist/Director in Translational Medicine for Cardiovascular disease.

You will lead early clinical development, design biomarker strategies, and guide biomarker platforms from PoC through Phase 4, interfacing across discovery, regulatory, and late-stage clinical teams. You will validate targets with clinical insights, drive early clinical plans for Lead Optimization, and ensure timely execution of Phase I studies with