Bioanalysis Scientist: MS Methods & CRO Collaboration

Scorpion Therapeutics; South San Francisco (CA); On-site; USD 110,000 - 143,000; Full time

Benefits offered by this job

401k

Healthcare coverage

ESPP

Job summary

Scorpion Therapeutics seeks a senior scientist to develop and qualify bioanalytical methods supporting discovery and development of novel therapeutics. You will measure biomarkers, drug concentrations, and anti-drug antibodies, and partner with CROs to optimize and transfer assays.

You will write and review study reports per IND/CTA/BLA/NDA guidelines, analyze data, and present findings to cross-functional teams, contributing to a robust regulatory-ready bioanalytical portfolio.

Qualifications

• Ph.D. in Analytical Chemistry or related field (or MS with 3+ years, or BS with 5+ years in biotech/pharma discovery)
• Hands-on bioanalytical method development, qualification/validation, and sample testing
• Experience with sample prep (protein precipitation, liquid-liquid extraction, SPE), chromatography, and triple-quadrupole MS
• Ligand binding assay experience (ELISA, MSD) preferred
• Familiarity with FDA, EMA, ICH guidance for regulated bioanalysis
• Experience with relevant bioanalytical tools and instrumentation
• Excellent critical thinking, communication, and cross-functional collaboration

Responsibilities

• Develop and qualify bioanalytical methods for discovery and development
• Conduct bioanalytical experiments to advance drug development portfolio
• Develop mass spectrometry methods for oligonucleotides and proteins
• Engage bioanalytical CROs for method optimization and transfer
• Prepare and finalize study reports per regulatory guidelines (IND/CTA/BLA/NDA)
• Analyze, interpret, and present data to project teams

Skills

Bioanalytical methods

Method validation

Sample testing

Ligand binding assays

Cross-functional collaboration

Communication skills

Education

PhD in Analytical Chemistry

MS in related field

BS with industry experience

Tools

Mass spectrometry

LC-MS/MS

Chromatography

Bioanalytical instruments

Job description

Scorpion Therapeutics seeks a senior scientist to develop and qualify bioanalytical methods supporting discovery and development of novel therapeutics. You will measure biomarkers, drug concentrations, and anti-drug antibodies, and partner with CROs to optimize and transfer assays.

You will write and review study reports per IND/CTA/BLA/NDA guidelines, analyze data, and present findings to cross-functional teams, contributing to a robust regulatory-ready bioanalytical portfolio.