Director, Theranostics and Radiation Science

AstraZeneca; Boston (MA); On-site; USD 203,709 - 305,564; Full time

Benefits offered by this job

401(k) plan

Paid vacation and holidays

Health benefits including medical, dental, and vision coverage

Job summary

AstraZeneca is seeking a Director, Theranostics and Radiation Science to lead the Radiation Sciences team in Boston. This role involves optimizing nuclear medicine imaging protocols, providing mentorship, and ensuring compliance with regulatory standards.

The ideal candidate has strong expertise in radiopharmaceuticals and technical proficiency in imaging techniques, with a minimum of 5 years industry experience. The position offers a competitive salary and comprehensive benefits.

Qualifications

• 5+ years of industry and/or clinical experience post residency.
• Knowledge of personalized dosimetry for radiopharmaceuticals.
• Experience with imaging and dosimetry packages.

Responsibilities

• Optimize nuclear medicine imaging protocols.
• Define requirements for imaging execution at clinical sites.
• Design and oversee quality control protocols.

Skills

Radiopharmaceutical dosimetry

Nuclear Medicine

Technical expertise in imaging techniques

Collaboration across teams

Education

BS degree in physical sciences

M.S. or Ph.D. in medical physics

Tools

Olinda

MIM

DICOM

PACS

Job description

At AstraZeneca, we’re building a different kind of biopharmaceutical company—one that redefines how transformational oncology medicines are conceived, developed, and delivered. Oncology Targeted Discovery accelerates impact by attacking cancer from multiple angles through innovative modalities, combinations, and precision regimens.

The Director, Theranostics and Radiation Science will play a key role in supporting the management, mentorship, and development of the Radiation Sciences team. You will help guide and support team members, fostering collaboration and professional growth within the team.

In addition to leadership, you will oversee key processes and work cross‑functionally with divisions across Imaging and Radioconjugate development, including but not limited to Clinical Operations, Preclinical Teams, Pharmacometrics, DMPK, and Regulatory Affairs. The role will also involve working with and helping manage external vendors and contractors to ensure the successful execution of ongoing and upcoming clinical trials.

This position requires a scientific and strategic mindset, strong technical background, and the ability to navigate complex projects while collaborating effectively across internal and external stakeholders.

Responsibilities

• Optimize and review nuclear medicine imaging protocols, including quality control parameters, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
• Define requirements and technical support for imaging execution at clinical sites, ensuring proper implementation and adherence to study protocols.
• Design and oversee quality control protocols, working with both internal teams and external partners for imaging review and processing.
• Provide training, mentorship, and problem‑solving support to internal and external clinical study teams to ensure study objectives are met.
• Perform image‑based, patient‑specific dosimetry calculations (internal dosimetry, not external beam radiation therapy [EBRT]).
• Collaborate with the Radiation Sciences team on imaging protocol optimization, ensuring alignment with best practices in QC, image acquisition, radiation dose management, and compliance with regulatory standards.
• Support regulatory compliance efforts related to radioactive materials, staying current with guidelines from regulatory and professional organizations (e.g., SNMMI, NRC, and international regulatory bodies).
• Contribute to research and discovery projects as needed, providing scientific and technical expertise to advance innovation in radiation sciences and molecular imaging.

Basic Qualifications

• BS degree in physical sciences, mathematics or other physical sciences followed by a graduate degree (M.S. or Ph.D.) in medical physics, physics or related scientific disciplines.
• Medical physics residency or Post Doctoral training with 5+ years of Industry and/or clinical experience (post residency).
• Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imaging and dosimetry packages is required.

Preferred Qualifications

• Board certification is preferred but not required.
• Prior industry experience is preferred but not required.
• Experience with radiopharmaceuticals, Nuclear Medicine, SPECT and PET imaging techniques, reconstruction, and camera quality control procedures are preferred.
• Strong concepts in radiation biology and radiation physics are preferred.
• Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS is required and client/server architectures and image processing is preferred.
• Understanding of imaging‑related project needs as expressed in a clinical study protocol.
• Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations (e.g., AAPM, SNMMI, NRC, and other country regulatory bodies).

The annual base salary for this position ranges from $203,709-$305,564. However, base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience.

Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.