Director, Strategy & BD | AI & Forecasting

Cytokinetics, Inc.; South San Francisco (CA); On-site; USD 236,000 - 275,000; Full time

Benefits offered by this job

Equity stock options

Restricted stock units (RSUs)

Health, dental, vision insurance

401k with employer match

Wellness stipends

Paid time off

Job summary

Cytokinetics, Inc. is seeking a Director of Strategy & Business Development in South San Francisco to lead top-down drug revenue forecasting, asset valuation, and enterprise planning while advancing the company’s AI initiatives and BD execution.

The role blends strategic analysis with hands-on financial modeling, requiring deep epidemiology-driven forecasting, DCF/rNPV analysis, and clear communication with senior leadership. On-site role with strong cross-functional collaboration.

Qualifications

• 4–7+ years in strategy consulting, investment banking, corporate strategy, or biotech/pharma BD.
• Proven ability to build top-down drug revenue forecasts and commercial models from epidemiology, pricing, and uptake.
• Strong quantitative and financial modeling skills including rNPV, DCF, and scenario analyses.
• Strategic thinker who can structure ambiguous problems into decision-ready recommendations.
• AI-capable: proficient with LLM tooling and lightweight automations; move use cases from POC to adoption.
• Excellent executive communication with senior leaders and the Board.
• Therapeutic fluency in cardiovascular or rare diseases is a plus.

Responsibilities

• Own first-pass top-down drug revenue forecasts translating epidemiology, pricing, and uptake into commercial forecasts.
• Develop valuation models (rNPV, scenario, sensitivity analyses) and assess out-licensing / deal opportunities.
• Translate forecasts into actionable implications and strategic recommendations for BD and leadership.
• Challenge commercial assumptions to improve forecast quality and speed of decision-making.
• Create reusable forecast and valuation templates to improve consistency.
• Support AI strategy initiatives and governance with cross-functional stakeholders.
• Partner with Finance, R&D and Commercial for integrated planning.

Skills

Forecasting

Financial modeling

AI tooling

Strategic thinking

Executive communication

Cardiovascular/biotech fluency

Education

MBA/PhD/MD or equivalent

Job description

Cytokinetics, Inc. is seeking a Director of Strategy & Business Development in South San Francisco to lead top-down drug revenue forecasting, asset valuation, and enterprise planning while advancing the company’s AI initiatives and BD execution.

The role blends strategic analysis with hands-on financial modeling, requiring deep epidemiology-driven forecasting, DCF/rNPV analysis, and clear communication with senior leadership. On-site role with strong cross-functional collaboration.