Director, Pharmacometrics — Oncology Modeling Leader

Avenzo Therapeutics, Inc.; San Diego (CA); Remoto; USD 234.000 - 250.000; Tempo pieno

Vantaggi offerti da questo lavoro

Healthcare benefits

401(k) plan

Paid vacation & holidays

Sick leave & disability insurance

Flexible spending accounts

Equity & bonuses

Descrizione del lavoro

Avenzo Therapeutics, Inc. is seeking a Director of Pharmacometrics in San Diego or Remote U.S. You will lead pharmacometrics strategies, apply population PK/PD and exposure–response modeling, and guide dose optimization from early trials through late-stage development.

Travel up to 15% may be required. You will collaborate with Clinical Pharmacology, Biometrics, and Regulatory teams to shape development plans and support global regulatory submissions and interactions.

Competenze

• PhD in pharmacometrics or related discipline with 8+ years of experience.
• Expertise in population PK/PD and exposure–response modeling.
• Experience with regulatory submissions and model-informed drug development.

Mansioni

• Lead pharmacometric strategies across oncology programs.
• Apply model-informed drug development to inform dose optimization and study design.
• Collaborate cross-functionally to support regulatory submissions and interactions.
• Oversee pharmacometric analyses for special populations and DDI considerations.
• Provide oversight of modeling platforms, workflows, and external partners.

Conoscenze

PhD in pharmacometrics

Population PK/PD

Exposure-response

Modeling & simulation

Regulatory submissions

Leadership

Formazione

PhD in pharmacometrics

Strumenti

NONMEM

Monolix

R

Descrizione del lavoro

Avenzo Therapeutics, Inc. is seeking a Director of Pharmacometrics in San Diego or Remote U.S. You will lead pharmacometrics strategies, apply population PK/PD and exposure–response modeling, and guide dose optimization from early trials through late-stage development.

Travel up to 15% may be required. You will collaborate with Clinical Pharmacology, Biometrics, and Regulatory teams to shape development plans and support global regulatory submissions and interactions.