Director, Pharmaceutical Sciences & Tech Lead

BridgeBio Pharma; Owens (OH); On-site; USD 267,000 - 332,000; Full time

Benefits offered by this job

401(k) match

Employee Stock Purchase Program

Hybrid work model

Comprehensive health benefits

Fertility & family-forming benefits

Job summary

BridgeBio Pharma is seeking a Pharmaceutical Sciences Team Lead to advance development across clinical and commercial programs, leading formulation, analytical, and manufacturing efforts with strong regulatory and quality oversight. You will guide cross-functional teams, manage external partners, and shape lifecycle strategies in a fast-paced environment.

The role requires a PhD and 15+ years in pharma/biotech, with executive communication skills and a track record of NDA/MAA submissions.

Qualifications

• PhD or equivalent advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biochemistry, or related scientific discipline preferred.
• 15+ years of progressive pharmaceutical or biotechnology industry experience with leadership responsibilities in Pharmaceutical Sciences, CMC, or Technical Operations.
• Experience leading multidisciplinary scientific teams in matrixed global organizations.
• Strong knowledge of pharmaceutical development, manufacturing, analytical development, regulatory expectations, and quality systems.
• Experience managing external manufacturing and development partners (CMOs/CDMOs/CROs).
• Strategic thinker with strong scientific and operational acumen.
• Exceptional communication and influencing skills with executive presence.
• Proven ability to drive alignment across complex cross-functional organizations.
• Strong decision-making and problem-solving capabilities in dynamic development environments.
• Prior experience in NDA/MAA submissions and regulatory approvals.
• Experience supporting commercial manufacturing and lifecycle management activities.
• Familiarity with global supply chain strategy and technical operations.
• Experience in both large pharmaceutical and emerging biotech environments preferred.
• Travel, as needed

Responsibilities

• Lead high-performing Pharmaceutical Sciences teams across multiple functional disciplines.
• Establish and drive organizational priorities, resource plans, and development goals.
• Identify program risks proactively and implement mitigation strategies.
• Provide scientific leadership for formulation, analytical, process development, manufacturing, and technology transfer.
• Partner with Regulatory, Clinical, Non-clinical, and Commercial teams to align priorities and execution.
• Represent Pharmaceutical Sciences in governance committees and executive reviews.
• Influence senior leadership decisions through data-driven recommendations.
• Collaborate with Regulatory Affairs on CMC strategy, risk mitigation, and agency responses.
• Interact with global health authorities and regulatory inspections as needed.
• Participate in due diligence and external scientific collaborations.
• Build relationships with external partners and vendors.
• Implement scalable systems, processes, and metrics to improve efficiency and quality.
• Foster an inclusive, performance-oriented culture aligned with leadership values.

Skills

Leadership

Strategic thinking

Regulatory knowledge

Cross-functional collaboration

Communication

Problem solving

Education

PhD in Pharmaceutical Sciences / related

Tools

External manufacturing partnerships

NDA/MAA submissions

Job description

BridgeBio Pharma is seeking a Pharmaceutical Sciences Team Lead to advance development across clinical and commercial programs, leading formulation, analytical, and manufacturing efforts with strong regulatory and quality oversight. You will guide cross-functional teams, manage external partners, and shape lifecycle strategies in a fast-paced environment.

The role requires a PhD and 15+ years in pharma/biotech, with executive communication skills and a track record of NDA/MAA submissions.