Director, MSAT

Scorpion Therapeutics; Cambridge (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Sana's is seeking a MSAT Director to lead technical support for PhaseI manufacturing of its stem cell-derived pancreatic islet cell therapy for type1 diabetes. The role emphasizes leadership, scientific rigor, and collaboration within a fast-paced cell therapy environment.

You will oversee process development, tech transfers, and batch execution, while collaborating with CDMOs and internal teams to ensure regulatory readiness and continuous improvement.

Qualifications

• 10+ years of experience in early-phase cell therapy manufacturing support.
• Experience working in cGMP and regulated environments.
• Knowledge of PSC culture and differentiation biology.
• Leadership experience with >3 direct reports.
• Strong problem-solving and technical writing skills; cross-disciplinary collaboration.

Responsibilities

• Manage a team supporting process development, technology transfers, batch execution, and documentation.
• Collaborate with external CDMOs and internal Quality, Regulatory, and Supply Chain teams.
• Author regulatory CMC documents (IND module3).
• Lead investigations, troubleshoot process issues, and drive continuous improvement.
• Ensure manufacturing readiness and technical compliance.

Skills

Leadership

Cross-disciplinary collaboration

Problem-solving

Technical writing

Education

Bachelor's degree in Chemical, Biological, or Biomedical Engineering

Job description

Role: MSAT Director leading technical support for PhaseI manufacturing of Sana's stem cell-derived pancreatic islet cell therapy for type1 diabetes.

Responsibilities

• manage a team supporting process development, technology transfers, batch execution, and documentation;
• collaborate with external CDMOs and internal Quality, Regulatory, and Supply Chain teams;
• author regulatory CMC documents (IND module3);
• lead investigations, troubleshoot process issues, and drive continuous improvement;
• ensure manufacturing readiness and technical compliance.

Requirements

• BSc in Chemical, Biological, or Biomedical Engineering;
• 10+ years of relevant experience including early-phase cell therapy manufacturing support;
• knowledge of cGMP, regulated environments, and PSC culture/differentiation biology;
• leadership experience with >3 direct reports;
• strong problem-solving, technical writing, and cross-disciplinary collaboration skills.

High-Value

cell therapy (PSC-derived pancreatic islet cells), PhaseI, regulatory document authoring, external manufacturing oversight, experience with GMP cleanroom environments, cell culture, and differentiation biology, and familiarity with analytical methods.

Work setup

involves ~25% travel in Canada; some weekend work; work in cleanroom settings.

The role emphasizes leadership, scientific rigor, and collaboration within a fast-paced, innovative cell therapy environment.