Director, Medical Informatics & Trial Data AI

Alzheon, Inc.; Framingham, Northern (MA, KY); Hybrid; USD 170,000 - 230,000; Full time

Job summary

Alzheon, Inc. is seeking a physician informatician to serve as Director, Medical Informatics, bridging clinical judgment, trial informatics, and advanced analytics inside our Data & AI organization.

You will work directly with clinical trial data across efficacy, safety, biomarker, imaging, and operational sources, keeping technology, data, and decisions grounded in clinical reality. This is a hands-on role for an MD who collaborates with Clinical Development, Clinical Operations, Data

Qualifications

• MD/DO or equivalent medical degree.
• Clinical trial data experience with regulatory exposure.
• Understanding of protocol design, endpoints, safety review, and data collection.
• Ability to communicate with clinicians, data managers, statisticians, programmers, and engineers.

Responsibilities

• Interpret efficacy, safety, cognitive, functional, biomarker, imaging, and operational data
• Provide medical judgment when emerging data signals require clinical context, interfacing with the broader medical, clinical and leadership teams to extract the right data and drive the right decisions
• Partner on endpoint definitions, subgroup analyses, and interpretation of treatment effects
• Define clinically meaningful data models, derived variables, and metadata across study sources
• Map protocol concepts and clinical questions to source data, SDTM, ADaM, and analysis outputs
• Identify implausible values, inconsistent definitions, missing context, and reconciliation issues
• Develop screening, eligibility, enrollment, retention, site-performance, and patient-journey analytics
• Translate clinical questions into AI use cases and review model outputs for clinical plausibility
• Support predictive and longitudinal modeling using multimodal clinical trial data
• Contribute to regulatory-grade analyses, integrated summaries, briefing materials, health-authority responses, and inspection readiness

Skills

Clinical data analysis

Communication with clinicians

Cross-functional collaboration

Medical informatics

Education

MD/DO or equivalent medical degree

Tools

EDC (Electronic Data Capture)

CDISC SDTM/ADaM

SQL

Python

R

SAS

Job description

Alzheon, Inc. is seeking a physician informatician to serve as Director, Medical Informatics, bridging clinical judgment, trial informatics, and advanced analytics inside our Data & AI organization.

You will work directly with clinical trial data across efficacy, safety, biomarker, imaging, and operational sources, keeping technology, data, and decisions grounded in clinical reality. This is a hands-on role for an MD who collaborates with Clinical Development, Clinical Operations, Data