Director, Site Operations & Strategic Execution

Denali Therapeutics; Salt Lake City (UT); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Competitive total rewards package, 401

Job summary

Scorpion Therapeutics in Salt Lake City seeks a Director, Site Operations & Strategic Execution to lead the site operating model, governance, and cross-functional execution across manufacturing, quality, supply chain, and engineering.

You will drive strategic initiatives, establish dashboards, manage risk, and mentor project leaders to scale operations for long-term commercial growth in a GMP environment.

Qualifications

• Bachelor’s degree plus 10+ years in biotech/pharma manufacturing, technical operations, supply chain, or operational leadership.
• GMP-regulated environment experience leading complex cross-functional operational initiatives.
• Strong understanding of biopharmaceutical manufacturing, commercialization readiness, and/or late-stage development.
• Ability to influence stakeholders without direct authority in fast-paced, ambiguous environments.
• Working knowledge of GMP and FDA/international regulatory requirements; ability to travel as required.

Responsibilities

• Lead and continuously improve the Site Operating Model, including governance, processes, decision frameworks, performance management, and cross-functional execution governance.
• Partner with Site Leadership and enterprise teams to align site execution with strategic priorities across manufacturing, quality, supply chain, engineering, and technical operations.
• Establish and manage governance forums, business reviews, metrics, dashboards, and reporting for visibility, accountability, risk management, and data-driven decisions.
• Lead strategic initiatives and continuous improvement to strengthen operational readiness, scalability, and long-term commercial growth.
• Coordinate cross-functional planning, resource prioritization, issue resolution, and mentor project leadership within the site.
• Identify operational risks, gaps, and inefficiencies; drive mitigation and continuous improvement.

Skills

Operational leadership

GMP knowledge

Executive communication

Cross-functional collaboration

Strategy & governance

KPI dashboards

Education

Bachelor’s degree in Engineering, Life Sciences, Operations, Supply Chain, Business, or related field

Job description

Director, Site Operations & Strategic Execution

Key Accountabilities / Core Responsibilities

• Lead and continuously improve the SLC Site Operating Model, including governance, operational processes, decision frameworks, performance management, and cross-functional execution governance.
• Partner with Site Leadership and enterprise teams to align site execution with strategic priorities across manufacturing, quality, supply chain, engineering, and technical operations.
• Establish and manage operational governance forums, business reviews, metrics, dashboards, and reporting processes for visibility, accountability, risk management, and data-driven decision-making.
• Lead strategic initiatives and continuous improvement efforts to strengthen operational readiness, scalability, organizational agility, and long-term commercial growth.
• Facilitate cross-functional coordination, resource planning and prioritization, issue resolution, and coach/mentor/develop project leadership and operational execution within the SLC organization.
• Identify operational risks, execution gaps, and inefficiencies; drive mitigation and continuous operational improvement.

Qualifications / Skills

• Bachelor’s degree in Engineering, Life Sciences, Operations, Supply Chain, Business, or related field; 10+ years in biotech/pharma manufacturing, technical operations, supply chain, or operational leadership.
• Advanced degree preferred.
• GMP-regulated environment experience leading complex cross-functional operational initiatives.
• Strong understanding of biopharmaceutical manufacturing, technical operations, commercialization readiness, and/or late-stage development.
• Experience with operational governance models, business processes, performance management systems, and operating cadences.
• Ability to influence stakeholders without direct authority; lead in fast-paced, ambiguous environments.
• Strong strategic thinking, operational problem-solving, and executive communication.
• Preferred: experience with operational metrics/dashboards; manufacturing readiness, PPQ execution, launch readiness, or operational scale-up.
• Working knowledge of GMP and FDA/international regulatory requirements; ability to travel as required.

Benefits (as stated)

• Competitive total rewards package including 401k, healthcare coverage, and ESPP.